Pteridines. 48. Utilization of 3,3-Dimethoxy-2-pyrrolidinopropene for the Synthesis of Folic Acid, N2'-Acetyl-7-folic Acid, and 5-Deaza-7-folic Acid

DOI: 10.1021/jo00320a034

Source and publish data:

Journal of Organic Chemistry p. 1394 - 1402 (1981)

Update date:2022-08-05

Topics:

Authors:

Taylor, Edward C.

Dumas, Donald J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00320a034

3,3-Dimethoxy-2-pyrrolidinopropene (7) is shown to be a useful intermediate for the synthesis of 6-formylpterin (1), 7-formylpterin (8), and 5-deaza-7-formylpterin (9).Thus, treatment of 7 with nitrosyl chloride followed by hydrolysis gives 1,1-dimethoxy-

Full text of DOI:10.1021/jo00320a034

Products guided by the article

Product name:7-formylpterin

Cas No:76282-56-9

R&D Labs maybe for 76282-56-9

Shandong Ailitong New Material Co.,Ltd

Contact:+86-536-3226266

Address:zhongjia village, putong town , qingzhou city,Shandong Province,China
Landz International Company Ltd.

Contact:0086-21-58891610

Address:985 Dongfang Road, Pudong, Shanghai 200122 China
Jingzhou TianHe Sci&Tech Chemical Co., Ltd.

Contact:86-716-8331612

Address:Jiangjin Road, #18, High-grade technology industries development district, Jingzhou city, Hubei province
Tocopharm Co., Ltd.

Contact:+86-021-6989-5597

Address:No.80 Yichuan Rd., Putuo District,Shanghai,P.R.China
Tianjin Dongchang Fine Chemical Industry Co., Ltd.

Contact:+86-22-29894595

Address:Economic Developing Zone, Ji County, Tianjin, China

Relevant to this article

A Comparison of Hypervalent Bond Polarizabilities in Sulfuranes (10-S-4 Species) and Persulfuranes (12-S-6 Species)

Doi:10.1021/ja00391a024
(1981)
Syntheses of 6,6a,7,8,9,10,10a,11-octahydro-11-oxodibenz[b,e]oxepins and 6,6a,7,8,9,10,10a,11-octahydro-11-oxodibenz[b,e]thiepins

Doi:10.1248/cpb.31.4312
(1983)
A controlled, iterative synthesis and the electronic properties of oligo[(p-phenyleneethynylene)-alt-(2,5-siloleneethynylene)]s

Doi:10.1021/ja047983a
(2004)
Organic Photochemistry with 6.7-ev Photons: γ,δ-Unsaturated Ketones

Doi:10.1021/ja00380a017
(1982)
(Z)-5-Benzylidene-2,5-dihydro-4-hydroxy-3-thiophenecarboxanilides: Synthesis and Isomerization into 5-Benzyl-4-hydroxy-3-thiophenecarboxanilides

Doi:10.1002/hlca.19800630623
(1980)
Synthesis of the 3',5'-cyclic phosphates from unprotected nucleosides

Doi:10.1055/s-1989-27150
(1989)

Article Doi