A new method for the preparation of (2R)-2-amino-5-phosphonopentanoic acid

DOI: 10.1016/S0040-4039(00)73684-7

Source and publish data:

Tetrahedron Letters p. 3289 - 3290 (1993)

Update date:2022-08-11

Topics:

Authors:

Muller Muller

Mann Mann

Taddei Taddei

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Article abstract of DOI:10.1016/S0040-4039(00)73684-7

A new and efficient synthesis of (2R)-2-amino-5-phosphonopentanoic acid(AP5) is reported. Our approach is based on a pseudo-Claisen [2,3] sigmatropic rearrangement of an alkyne phosphite.

Full text of DOI:10.1016/S0040-4039(00)73684-7

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