Journal of Organic Chemistry p. 6291 - 6299 (2015)
Update date:2022-08-11
Topics:
Murugavel, Govindarasu
Punniyamurthy, Tharmalingam
Microwave-assisted copper-catalyzed four-component tandem synthesis of 3-N-sulfonylamidine coumarins has been accomplished by the coupling of salicylaldehydes, propiolates, sulfonyl azides, and secondary amines. This one-pot protocol affords an effective route for the construction of functionalized coumarin structural frameworks in a single operation with moderate to high yields.
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