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GLYCIDALDEHYDE

  • Name GLYCIDALDEHYDE
  • EINECSN/A
  • CAS No. 765-34-4
  • Density1.417g/cm3
  • PSA29.60000
  • LogP-0.41590
  • SolubilityN/A
  • Melting Point-62°C
  • FormulaC3H4 O2
  • Boiling Point112.5°C at 760 mmHg
  • Molecular Weight72.0636
  • Flash Point29.921°C
  • Transport InformationN/A
  • Appearancewhite to light yellow crystal powde
  • SafetyConfirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, skin contact, intraperitoneal, and intravenous routes. Moderately toxic by inhalation. Human systemic effects by inhalation: changes in central nervous system electrical activity, olfactory changes, and excitement. Mutation data reported. A human eye irritant. Powerful skin sensitizer and mucous membrane irritant. Flammable when exposed to heat, flame, or oxidizing materials. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALDEHYDES.
  • Risk CodesR11
  • Molecular Structure
    Molecular Structure of 765-34-4 (GLYCIDALDEHYDE)
  • Hazard SymbolsC,Xi
  • SynonymsC,Xi
  • Article Data16

GLYCIDALDEHYDE Chemical Properties

Glycidaldehyde is also named as 2,3-Epoxypropionaldehyde;2,3-epoxy-1-propanal;2,3-epoxypropanal;2,3-epoxy-propionaldehyd;epihydrinaldehyde;epihydrinealdehyde;formyloxiran,and so on.

Molecular Formula: C3H4O2
Molecular Weight: 72.06
EINECS: 212-143-8
Melting point: -61.8 °C
Boiling point: 112-113 °C
Density: 1.14(20 °C)

GLYCIDALDEHYDE Uses

Glycidaldehyde is commonly used in cotton processing, leather tanning and  protein coagulation as the chemical intermediates and cross-linking agent.

GLYCIDALDEHYDE Toxicity Data With Reference

1.   

eye-hmn 1 ppm/5M MOD

   AEHLAU    Archives of Environmental Health. 2 (1961),23.
2.   

mmo-esc 10 µg/plate

   ENMUDM    Environmental Mutagenesis. 6 (Suppl 2)(1984),1.
3.   

mma-esc 33,300 ng/plate

   ENMUDM    Environmental Mutagenesis. 6 (Suppl 2)(1984),1.
4.   

skn-rbt 100 mg/24H MOD

   85JCAE    Prehled Prumyslove Toxikologie; Organicke Latky Marhold, J.,Prague, Czechoslovakia.: Avicenum,1986,770.
5.   

scu-rat TDLo:13 g/kg/77W-I:CAR

   JNCIAM    Journal of the National Cancer Institute. 39 (1967),1213.
6.   

ihl-hmn TCLo:5 ppm:BRN,EYE,CNS

   34ZIAG    Toxicology of Drugs and Chemicals ,Deichmann, W.B.,New York, NY.: Academic Press, Inc.,1969,289.
7.   

orl-rat LDLo:50 mg/kg

   AJHYA2    American Journal of Hygiene. 76 (1962),209.
8.   

ihl-rat LCLo:251 ppm/4H

   14CYAT    Industrial Hygiene and Toxicology. 2 (1963),1636.
9.   

ipr-mus LD50:200 mg/kg

   JJIND8    JNCI, Journal of the National Cancer Institute. 62 (1979),911.
10.   

skn-rbt LD50:249 mg/kg

   AEHLAU    Archives of Environmental Health

RTECS: MB3150000

GLYCIDALDEHYDE Consensus Reports

IARC Cancer Review: Group 2B IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 11 , 1976,p. 175.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

GLYCIDALDEHYDE Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, skin contact, intraperitoneal, and intravenous routes. Moderately toxic by inhalation. Human systemic effects by inhalation: changes in central nervous system electrical activity, olfactory changes, and excitement. Mutation data reported. A human eye irritant. Powerful skin sensitizer and mucous membrane irritant. Flammable when exposed to heat, flame, or oxidizing materials. When heated to decomposition it emits acrid smoke and irritating fumes.

Risk Statements: 11
Safety Statements:  9-16-33
RIDADR:  2622
HazardClass:  3.1
PackingGroup:  II

GLYCIDALDEHYDE Standards and Recommendations

DOT Classification:  3; Label: Flammable Liquid, Poison
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