Hexafluoroacetone(684-16-2) is a chemical compound with the formula CF₃-CO-CF₃. It is structurally similar to acetone, however its reactivity is markedly different. It comes in the form of a colourless, hygroscopic, nonflammable, highly reactive gas characterized by a musty odour. The most common form of this substance is hexafluoroacetone sesquihydrate (1.5 H₂O), which is a gem-diol.
IUPAC Name: 1,1,1,3,3,3-hexafluoropropan-2-one
Molecular formula: C₃F₆O
Molar mass: 166.02 g/mol
Appearance: Colorless gas
Density: 1.32 g/ml, liquid
Melting point: -129 °C (144 K)
Boiling point: -28 °C (245 K)
Solubility in water: Reacts with water
Other names: perfluoroacetone, acetone hexafluoride, perfluoro-2-propanone
The Structure of HEXAFLUOROACETONE(684-16-2):

Hexafluoroacetone(684-16-2) is mostly employed in organic synthesis, but it is also the main chemical intermediate used in the production of hexafluoroisopropanol, as well as polymethyl methacrylates and polyesters for textile coating. Hexafluoroacetone(684-16-2) can be employed as a solvent for acetal resins, polyamides and polyglycolide or as a polymer adhesive.

Hexafluoroacetone(684-16-2) is prepared in a two step process from perfluoropropene. In the first step KF catalyzes the reaction of the alkene with elemental sulfur to give the 1,3-dithete [(CF₃)₂CS]₂. This species is then oxidized by iodate to give (CF₃)₂CO.

Reported in EPA TSCA Inventory.

A poison by ingestion. Moderately toxic by inhalation. A poisonous irritant to the skin, eyes, and mucous membranes. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits toxic fumes of F⁻. See also FLUORINE and FLUORIDES.
Hazard Codes: T
Risk Statements: 60-14-23/24/25-34-63
60:  May impair fertility 
14:  Reacts violently with water 
23/24/25:  Toxic by inhalation, in contact with skin and if swallowed 
34:  Causes burns 
63:  Possible risk of harm to the unborn child 
Safety Statements: 53-26-28-36-45-7/9
53:  Avoid exposure - obtain special instruction before use 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing 
45:  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
7/9:  Keep container tightly closed and in a well-ventilated place 
RIDADR: UN 2420 2.3
WGK Germany: 3
RTECS: UC2450000
Hazard Note: Highly Toxic
TSCA: T
HazardClass: 2.3

OSHA PEL: TWA 0.1 ppm (skin)
ACGIH TLV: TWA 0.1 ppm (skin)
DOT Classification:  2.3; Label: Poison Gas