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Heptachlor epoxide

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Name

Heptachlor epoxide

EINECS 213-831-0
CAS No. 1024-57-3 Density 1.91g/cm3
PSA 12.53000 LogP 4.45270
Solubility N/A Melting Point N/A
Formula C10H5 Cl7 O Boiling Point 425.5°Cat760mmHg
Molecular Weight 389.32 Flash Point 162.2°C
Transport Information N/A Appearance N/A
Safety Confirmed carcinogen with experimental carcinogenic data. Poison by ingestion and intravenous routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl. See also HEPTACHLOR. Risk Codes R25; R33; R40; R50/53; R39/23/24/25; R23/24/25; R11
Molecular Structure Molecular Structure of 1024-57-3 (Epoxyheptachlor) Hazard Symbols Confirmed carcinogen and poison by ingestion. TLV: 0.05 mg/m3; animal carcinogen.
Synonyms

2,5-Methano-2H-indeno[1,2-b]oxirene,2,3,4,5,6,7,7-heptachloro-1a,1b,5,5a,6,6a-hexahydro-, (1aa,1bb,2a,5a,5ab,6b,6aa)-;4,7-Methanoindan,1,4,5,6,7,8,8-heptachloro-2,3-epoxy-3a,4,7,7a-tetrahydro- (8CI);(?à)-cis-Heptachlor epoxide;ENT25584;Epoxyheptachlor;GPKh epoxide;HCE;HE;Hepox;Heptachlor cis-oxide;Heptachlor epoxide;Heptachlor epoxide B;Heptachlor exo-epoxide;Heptepoxide;Velsicol 53CS17;cis-Heptachlor epoxide;

 

Heptachlor epoxide Chemical Properties

Empirical Formula: C10H5Cl7O
Molecular Weight: 389.3171 
EINECS: 213-831-0 
Index of Refraction: 1.661
Density: 1.91 g/cm3
Flash Point: 162.2 °C
Enthalpy of Vaporization: 65.39 kJ/mol
Boiling Point: 425.5 °C at 760 mmHg
Vapour Pressure: 4.71E-07 mmHg at 25 °C 
Structure of Heptachlor epoxide (CAS NO.1024-57-3):
            
Product Categories of Heptachlor epoxide (CAS NO.1024-57-3): Baby Food Directives;Cyclodienes;Insecticides;Method Specific;Method Specific;Alpha sort;Oeko-Tex Standard 100;Pesticides & Metabolites

Heptachlor epoxide Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cattle LDLo oral 5mg/kg (5mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Journal of Economic Entomology. Vol. 52, Pg. 1127, 1959.
mouse LD50 intracrebral 8mg/kg (8mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Toxicology Letters. Vol. 60, Pg. 289, 1992.
mouse LD50 oral 39mg/kg (39mg/kg)   Agricultural Research Service, USDA Information Memorandum. Vol. 20, Pg. 27, 1966.
mouse LDLo intravenous 10mg/kg (10mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 107, Pg. 266, 1953.
rabbit LD50 oral 144mg/kg (144mg/kg)   "Pesticides Symposia; Collection of Papers Presented at the Sixth & Seventh Inter-American Conferences on Toxicology and Occupational Medicine, Miami, FL," Miami, FL, J.L. Halos, 1968-70Vol. 6, Pg. 231, 1968/1970.
rat LD50 oral 15mg/kg (15mg/kg)   Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 52(2), Pg. 93, 1987.

Heptachlor epoxide Consensus Reports

IARC Cancer Review: Human Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 20 , 1979,p. 129.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 5 , 1974,p. 173.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Limited Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 20 , 1979,p. 129.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

Heptachlor epoxide Safety Profile

Confirmed carcinogen with experimental carcinogenic data. Poison by ingestion and intravenous routes. Human mutation data reported. When heated to decomposition it emits toxic fumes of Cl. See also HEPTACHLOR.
 

Hazard Codes of Heptachlor epoxide (CAS NO.1024-57-3): ToxicTDangerousNFlammableF
Risk Statements: 25-33-40-50/53-39/23/24/25-23/24/25-11 
R11:Highly flammable. 
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed. 
R25 :Toxic if swallowed. 
R33:Danger of cumulative effects. 
R39:Danger of very serious irreversible effects. 
R40:Limited evidence of a carcinogenic effect.
Safety Statements: 36/37-45-60-61-16-7 
S7:Keep container tightly closed. 
S16:Keep away from sources of ignition. 
S36/37:Wear suitable protective clothing and gloves. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) 
S60:This material and its container must be disposed of as hazardous waste. 
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.

Heptachlor epoxide Standards and Recommendations

ACGIH TLV: TWA 0.05 mg/m3 (skin); Animal Carcinogen

Heptachlor epoxide Specification

 Heptachlor epoxide ,its cas register number is 1024-57-3. It also can be called 4,7-Methanoindan, 1,4,5,6,7,8,8-heptachloro-2,3-epoxy-3a,4,7,7a-tetrahydro- ; 2,3,4,5,6,7,7-Heptachloro-1a,1b,5,5a,6,6a-hexahydro-2,5-methano-2H-indeno[1,2-b]oxirene ; and 1,6,8,9,10,11,11-Heptachlor-4-oxatetracyclo[6.2.1.0~2,7~.0~3,5~]undec-9-en .

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