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Name	LEVOBUNOLOL HYDROCHLORIDE	EINECS	248-725-3
CAS No.	27912-14-7	Density	N/A
PSA	58.56000	LogP	3.52630
Solubility	N/A	Melting Point	209-211°
Formula	C₁₇H₂₅NO₃^.HCl	Boiling Point	464.4 °C at 760 mmHg
Molecular Weight	327.89	Flash Point	234.7 °C
Transport Information	N/A	Appearance	N/A
Safety		Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	(-)-5-[3-(tert-butylamino)-2-hydroxypropoxy]-3,4-dihydronaphthalene-1(2H)-one hydrochloride;Vistagan;(2S)-N-(tert-butyl)-2-hydroxy-3-[(5-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)oxy]propan-1-aminium chloride;Betagan (TN);Prestwick_167;Levobunolol hydrochloride (JAN/USP);1(2H)-Naphthalenone,5-[(2S)-3-[(1,1- dimethylethyl)amino]-2-hydroxypropoxy]-3,4- dihydro-,hydrochloride;Levobunolol hydrochloride [USAN];(-)-3,4-Dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-1(2H)-naphthalenone hydrochloride;1(2H)-Naphthalenone, 5-(3-((1,1-dimethylethyl)amino)-2-hydroxypropoxy)-3,4-dihydro-, hydrochloride, (-)-;Betagan;

LEVOBUNOLOL HYDROCHLORIDE Chemical Properties

Product Name: Levobunolol hydrochloride (CAS NO.27912-14-7)

Molecular Formula: C₁₇H₂₆ClNO₃
Molecular Weight: 327.85g/mol
Mol File: 27912-14-7.mol
Einecs: 248-725-3
Appearance: Glaucoma drug
Boiling point: 464.4 °C at 760 mmHg
Flash Point: 234.7 °C
Enthalpy of Vaporization: 76.47 kJ/mol
Vapour Pressure: 2.01E-09 mmHg at 25°C
H-Bond Donor: 3
H-Bond Acceptor: 4

LEVOBUNOLOL HYDROCHLORIDE Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	100mg/kg (100mg/kg)		General Pharmacology. Vol. 17, Pg. 373, 1986.
hamster	LD50	oral	435mg/kg (435mg/kg)		General Pharmacology. Vol. 17, Pg. 373, 1986.
man	TDLo	ocular	8571nL/kg/9W- (8571mL/kg)	BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" CARDIAC: PULSE RATE	American Heart Journal. Vol. 127, Pg. 689, 1994.
mouse	LD50	intravenous	78mg/kg (78mg/kg)		General Pharmacology. Vol. 17, Pg. 373, 1986.
mouse	LD50	oral	1220mg/kg (1220mg/kg)		"Pharmacology of Antihypertensive Drugs," Scriabine, A., ed., New York, Raven Press, 1980Vol. -, Pg. 317, 1980.
rat	LD50	intravenous	25mg/kg (25mg/kg)		General Pharmacology. Vol. 17, Pg. 373, 1986.
rat	LD50	oral	700mg/kg (700mg/kg)		General Pharmacology. Vol. 17, Pg. 373, 1986.
women	TDLo	ocular	1uL/kg/12H-I (0.001mL/kg)	LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION	Medical Journal of Australia. Vol. 161, Pg. 576, 1994.

LEVOBUNOLOL HYDROCHLORIDE Safety Profile

A poison by ingestion and intravenous routes. Questionable carcinogen with experimental neoplastigenic data reported. When heated to decomposition it emits toxic vapors of NO_x and HCl.

LEVOBUNOLOL HYDROCHLORIDE Specification

Levobunolol hydrochloride ,its CAS NO. is 27912-14-7,the synonyms is (-)-3,4-Dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-1(2h)-naphthalenone ; (-)-Rochlorid;3,4-dihydro-5-(3-(tert-butylamino)-2-hydroxypropoxy)-1(2h)-naphthalenonhyd ; Betagan;gotensin ; l-Bunololhydrochloride ; Vistagan ; W7000a .

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