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Name	Lactose	EINECS	200-559-2
CAS No.	63-42-3	Density	1.76 g/cm³
PSA	197.37000	LogP	-5.55460
Solubility	5-10 g/100 mL at 20 °C in water	Melting Point	222.8 °C
Formula	C₁₂H₂₂O₁₁	Boiling Point	667.9 °C at 760 mmHg
Molecular Weight	342.3	Flash Point	357.8 °C
Transport Information	N/A	Appearance	white crystals or powder
Safety	24/25	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	4-O-beta-D-Galactopyranosyl-D-glucose;D-Glucose, 4-O-beta-D-galactopyranosyl-;Galactinum;Fast-flo Lactose;

Lactose Synthetic route

: 492-61-5
β-D-glucose

: 5435-44-9, 22243-66-9
(E)-3-Ureido-but-2-enoic acid ethyl ester

: 63-42-3
D-(+)-lactose

Conditions

Conditions	Yield
at 175℃; under 15 Torr;

: 64-19-7
acetic acid

: 41263-94-9
2’-fucosyllactose

A: 2438-80-4
L-Fucose

B: 63-42-3
D-(+)-lactose

: 3616-19-1, 5328-50-7, 5346-90-7, 6291-42-5, 6920-00-9, 20764-63-0, 20880-60-8, 20880-65-3, 22352-19-8, 23973-20-8, 32447-69-1, 34213-32-6, 52554-32-2, 53956-64-2, 56907-29-0, 56994-12-8, 56994-13-9, 57128-38-8, 67650-36-6, 68036-17-9, 68036-19-1, 78215-50-6, 78215-51-7, 79549-48-7, 80446-82-8, 85249-04-3, 93221-83-1, 93779-27-2, 111407-83-1, 111407-84-2, 111407-85-3, 120328-65-6, 123809-59-6, 132341-46-9, 132341-47-0, 132341-49-2, 145307-94-4
1',2',3',6',2,3,4,6-octa-O-acetyl-β-D-lactose

: 63-42-3
D-(+)-lactose

Conditions

Conditions	Yield
With methanol; barium methoxide

: 492-61-5
β-D-glucose

β-D-galactose: β-D-galactose

: 63-42-3
D-(+)-lactose

Conditions

Conditions	Yield
With zinc(II) chloride at 175℃; under 15 Torr;

: 3068-32-4
1-bromo-1-deoxy-2,3,4,6-tetra-O-acetyl-a-D-galactopyranoside

O2,O3;O5,O6-diisopropylidene-D-glucose-diethylacetal: O2,O3;O5,O6-diisopropylidene-D-glucose-diethylacetal

: 63-42-3
D-(+)-lactose

Conditions

Conditions	Yield
With chloroform; iodine; silver(l) oxide anschl. mit methanol. NaOH und dann mit wss. Essigsaeure;

: 7647-01-0
hydrogenchloride

: 41263-94-9
2’-fucosyllactose

A: 2438-80-4
L-Fucose

B: 63-42-3
D-(+)-lactose

: 909878-64-4
meso-erythritol

: 87-69-4
L-Tartaric acid

A: 488-73-3
(+)-proto-quercitol

B: 57-50-1
Sucrose

C: 63-42-3
D-(+)-lactose

D pinitol: pinitol

...Expand

: 63-42-3
D-(+)-lactose

: 96-82-2, 534-41-8, 534-42-9, 51267-45-9, 58459-39-5, 69728-97-8
lactobionic acid

Conditions

Conditions	Yield
With oxygen for 2h; Reagent/catalyst;	100%
With sodium hydroxide; palladium dichloride; potassium hexacyanoferrate(III) In water at 35℃; Rate constant; Thermodynamic data; Eact, ΔS(excit.), ΔH(excit.), ΔG(excit.);
With sodium hydroxide; potassium hexacyanoferrate(III) In water at 35℃; Rate constant; Thermodynamic data; Eact, ΔS(excit.), ΔH(excit.), ΔG(excit.);

: 2016-42-4
tetradecylamine

: 63-42-3
D-(+)-lactose

: N-tetradecyl lactosamine

Conditions

Conditions	Yield
at -10℃;	92%

: 124-22-1
n-Dodecylamine

: 63-42-3
D-(+)-lactose

: N-dodecyl lactosamine

Conditions

Conditions	Yield
at -10℃;	90%

Lactose Chemical Properties

Molecular Structure:

Molecular Formula: C₁₂H₂₂O₁₁
Molecular Weight: 342.30
IUPAC Name: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-[(2R,3S,4R,5R,6R)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxane-3,4,5-triol
Synonyms of Lactose (CAS NO.200-559-2): (+)-Lactose ; 4-(beta-D-Galactosido)-D-glucose ; 4 -O-beta-D-Galactopyranosyl-D-glucose ; D-Lactose ; Lactose, anhydrous
CAS NO: 200-559-2
EINECS: 200-559-2
H bond acceptors: 11
H bond donors: 8
Freely Rotating Bonds: 12
Polar Surface Area: 101.53 Å²
Index of Refraction: 1.652
Molar Refractivity: 70.8 cm³
Molar Volume: 193.6 cm³
Surface Tension: 110.8 dyne/cm
Density: 1.76 g/cm³
Flash Point: 357.8 °C
Enthalpy of Vaporization: 112.36 kJ/mol
Boiling Point: 667.9 °C at 760 mmHg
Vapour Pressure: 1.08E-20 mmHg at 25°C
Melting Point: 222.8°C
Water Solubility: 5-10 g/100 mL at 20 ºC
Stability: Stable. Incompatible with strong oxidizing agents.
Appearance: white crystals or powder
Product Categories of Lactose (CAS NO.200-559-2): Dextrins、Sugar & Carbohydrates

Lactose Uses

Lactose (CAS NO.200-559-2) is used in stout beers rarely to sweeten the beer and is non-fermentable in beer.

Lactose Production

Lactose (CAS NO.200-559-2) is little fermented by baker's yeast and during brewing, which may be used to advantage. It is extracted from sweet or sour whey.

Lactose Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Source
dog	LDLo	intravenous	1500mg/kg (1500mg/kg)	"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935.
rat	LD50	intraperitoneal	> 10gm/kg (10000mg/kg)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.
rat	LD50	oral	> 10gm/kg (10000mg/kg)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.
rat	LD50	subcutaneous	> 5gm/kg (5000mg/kg)	Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.

Lactose Consensus Reports

Reported in EPA TSCA Inventory.

Lactose Safety Profile

WGK Germany: 2
RTECS: OD9625000
Moderately toxic by intravenous route. Questionable carcinogen with experimental tumorigenic and teratogenic data. Mixtures with oxidants (e.g., potassium chlorate, potassium nitrate, or potassium perchlorate) may be explosion hazards. When heated to decomposition it emits acrid smoke and irritating fumes.

Lactose Specification

Lactose is a sugar that is found most notably in milk. The name comes from the Latin word for milk, plus the -ose ending used to name sugars.

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