- Meglumine
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| Name |
Meglumine diatrizoate |
EINECS | N/A |
| CAS No. | 131-49-7 | Density | g/cm3 |
| PSA | 215.66000 | LogP | 1.44700 |
| Solubility | N/A | Melting Point |
189-193° (dec) |
| Formula | C11H9I3N2O4•C7H17NO5 | Boiling Point | 614.1°Cat760mmHg |
| Molecular Weight | 809.133 | Flash Point | 325.2°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intracerebral route. Human systemic effects by subcutaneous route: kidney damage and reduced urine volume. When heated to decomposition it emits toxic fumes of I− and NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
3,5-diacetamido-2,4,6-triiodo-benzoicacicompd.with1-deoxy-1-(methylam;amidotrizoatemeglumine;angiografin;cardiografin;d-;d-glucitol,1-deoxy-1-(methylamino)-,3,5-bis(acetylamino)-2,4,6-triiodobenzo;diatrizoatemethylglucamine;gastrografin |
Meglumine diatrizoate Chemical Properties
IUPAC Name: 3,5-Diacetamido-2,4,6-triiodobenzoic acid; (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
The MF of Meglumine diatrizoate (CAS NO.131-49-7) is C18H26I3N3O9.
The MW of Meglumine diatrizoate (CAS NO.131-49-7) is 809.13.
Synonyms of Meglumine diatrizoate (CAS NO.131-49-7): Diatrizoic acid methylglucamine
Product Categories: Cell Separation (Centrifugation) Media;Hematology and Histology
Flash Point: 325.2 °C
Boiling Point: 614.1 °C
EINECS: 205-024-7
Meglumine diatrizoate Uses
Meglumine diatrizoate (CAS NO.131-49-7) is used as fine chemicals, pharmaceutical intermediates.
Meglumine diatrizoate Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| man | TDLo | subcutaneous | 214mg/kg (214mg/kg) | KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI KIDNEY, URETER, AND BLADDER: INTERSTITIAL NEPHRITIS KIDNEY, URETER, AND BLADDER: URINE VOLUME DECREASED | "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 392, 1969. |
| mouse | LD50 | intracrebral | 80mg/kg (80mg/kg) | BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: EXCITEMENT | Therapie. Vol. 26, Pg. 595, 1971. |
| mouse | LD50 | intravenous | 21200mg/kg (21200mg/kg) | Drugs in Japan Vol. 6, Pg. 32, 1982. | |
| rat | LD50 | intravenous | 14565mg/kg (14565mg/kg) | AJR, American Journal of Roentgenology. Vol. 142, Pg. 619, 1984. | |
| rat | LD50 | parenteral | 44504mg/kg (44504mg/kg) | AJR, American Journal of Roentgenology. Vol. 142, Pg. 619, 1984. | |
| rat | LD50 | unreported | 19500mg/kg (19500mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 26, Pg. 921, 1984 |
Meglumine diatrizoate Safety Profile
Poison by intracerebral route. Human systemic effects by subcutaneous route: kidney damage and reduced urine volume. When heated to decomposition it emits toxic fumes of I− and NOx.
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