- Methyl 1-Benzyl-5-oxopyrrolidine-3-carboxylate
- Methyl (((methoxymethylphosphinothioyl)thio)acetyl)methylcarbamate
- Methyl (+)-(3R)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methanesulfonylamino)pyrimidin-5-yl]-3-hydroxy-5-oxo-(6E)-heptenoate
- Methyl (2-amino-5-methyl-1,3-thiazol-4-yl)acetate
- Methyl (2-chloromethyl)oxazole-4-carboxylate
- Methyl (2E)-3-(4-methylphenyl)propenoate
- Methyl (2E)-3-cyclohexylprop-2-enoate
- Methyl (2R)-2-[(tert-butoxycarbonyl)amino]-3-iodopropanoate
- Methyl (2R)-2-[4-(2,4-dichlorophenoxy)phenoxy]propanoate
- Methyl (2R)-2-amino-2-cyclohexylethanoate hydrochloride
- 36052-25-23-Pyridinecarboxylicacid, 5-amino-, methyl ester
- 36052-26-32-Pyridinecarboxylicacid, 6-amino-, methyl ester
- 36052-27-42-Pyridinecarboxylicacid, 3-amino-, methyl ester
- 36052-37-64H-1-Benzopyran-4-one,2,3-dihydro-7-hydroxy-5-methoxy-2-phenyl-, (2S)-
- 360-53-21-Propene,1,3,3,3-tetrafluoro-1-methoxy-2-(trifluoromethyl)-
- 36054-00-96-Methyl-2,3-dihydroquinolin-4(1H)-one
- 360-54-3Propanoic acid,3,3,3-trifluoro-2-(trifluoromethyl)-, methyl ester
- 360561-52-02-Piperazinone,1-(4-chlorophenyl)-, hydrochloride (1:1)
- 3605-65-0Aluminum,(2-butanolato)bis(2-propanolato)-
- 360573-13-3L-Tryptophan,N-[(5-methyl-2-furanyl)carbonyl]-
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
Methyl 6-aminonicotinate |
EINECS | 629-051-2 |
| CAS No. | 36052-24-1 | Density | 1.238 g/cm3 |
| PSA | 65.21000 | LogP | 1.03160 |
| Solubility | N/A | Melting Point |
158-162 °C(lit.) |
| Formula | C7H8N2O2 | Boiling Point | 304.5 °C at 760 mmHg |
| Molecular Weight | 152.153 | Flash Point | 137.9 °C |
| Transport Information | UN 2811 | Appearance | off-white solid |
| Safety | 26-36-36/37 | Risk Codes | 36/37/38-20/21/22 |
| Molecular Structure |
|
Hazard Symbols |
 Xi,  Xn
|
| Synonyms |
Nicotinicacid, 6-amino-, methyl ester (6CI,8CI);2-Amino-5-(methoxycarbonyl)pyridine;3-Pyridinecarboxylicacid, 6-amino-, methyl ester;6-Aminopyridine-3-carboxylic acid methylester;Methyl 2-aminopyridine-5-carboxylate;6-Aminonicotinic acid methyl ester;Methyl6-aminopyridine-3-carboxylate; |
Article Data | 30 |
Methyl 6-aminonicotinate Synthetic route
| Conditions | Yield |
|---|---|
| With hydrogenchloride for 18h; Reflux; | 98% |
| With thionyl chloride at 80℃; for 12h; Inert atmosphere; | 89% |
| With sulfuric acid at 0 - 80℃; | 81.5% |
- 3167-49-5
6-aminonicotinic acid
- 18107-18-1
diazomethyl-trimethyl-silane
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| In methanol; chloroform; cyclohexane at 20℃; for 1h; | 66% |
| With acetic acid In methanol; chloroform |
- 21550-48-1
6-(acetylamino)pyridine-3-carboxylic acid
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| With hydrogenchloride; methanol |
- 1603-41-4
(5-methyl-pyridin-2-yl)amine
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: acetic acid 2: aqueous KMnO4 3: methanol; HCl View Scheme |
- 4931-47-9
N-(5-methylpyridin-2-yl)acetamide
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: aqueous KMnO4 2: methanol; HCl View Scheme |
- 3167-49-5
6-aminonicotinic acid
- 36052-24-1
methyl 6-aminonicotinoate
| Conditions | Yield |
|---|---|
| With hydrogenchloride In methanol; water | |
| With sulfuric acid In methanol; water-EtOAc | |
| With thionyl chloride In methanol; water |
| Conditions | Yield |
|---|---|
| In hydrogenchloride; methanol; water |
| Conditions | Yield |
|---|---|
| In hydrogenchloride; methanol; water | |
| In hydrogenchloride; methanol; water | |
| In hydrogenchloride; methanol; water | |
| In hydrogenchloride; methanol; water | |
| In hydrogenchloride; methanol; water |
| Conditions | Yield |
|---|---|
| In methanol |
- 36052-24-1
methyl 6-aminonicotinoate
- 24424-99-5
di-tert-butyl dicarbonate
- 144186-11-8
methyl 6-<(tert-butyloxycarbonyl)amino>nicotinoate
| Conditions | Yield |
|---|---|
| With dmap In tetrahydrofuran at 20℃; | 100% |
| With dmap In acetonitrile for 4h; Ambient temperature; | 79% |
| With dmap In acetone; tert-butyl alcohol for 20h; | 78% |
Methyl 6-aminonicotinate Chemical Properties
The molecular structure of 6-Aminonicotinic acid methyl ester (CAS NO.36052-24-1):
IUPAC Name: Methyl 6-aminopyridine-3-carboxylate
Molecular Weight: 152.15062 g/mol
Molecular Formula: C7H8N2O2
Density: 1.238 g/cm3
Melting Point: 158-162 °C(lit.)
Boiling Point: 304.5 °C at 760 mmHg
Flash Point: 137.9 °C
Index of Refraction: 1.57
Molar Refractivity: 40.35 cm3
Molar Volume: 122.8 cm3
Surface Tension: 53.4 dyne/cm
Enthalpy of Vaporization: 54.48 kJ/mol
Vapour Pressure: 0.000872 mmHg at 25 °C
XLogP3: 1.7
H-Bond Donor: 1
H-Bond Acceptor: 4
Rotatable Bond Count: 2
Tautomer Count: 4
Exact Mass: 152.058578
MonoIsotopic Mass: 152.058578
Topological Polar Surface Area 65.2
Heavy Atom Count 11
Canonical SMILES: COC(=O)C1=CN=C(C=C1)N
InChI: InChI=1S/C7H8N2O2/c1-11-7(10)5-2-3-6(8)9-4-5/h2-4H,1H3,(H2,8,9)
InChIKey: JACPDLJUQLKABC-UHFFFAOYSA-N
Product Categories: Amines; blocks; Carboxes; Pyridines; pharmacetical; Esters; Heterocycles; Heterocyclic Building Blocks
Methyl 6-aminonicotinate Uses
6-Aminonicotinic acid methyl ester (CAS NO.36052-24-1) is used in ointments for treatment of psoriasis.
Methyl 6-aminonicotinate Safety Profile
Hazard Codes: 
Xi, 
Xn
Risk Statements: 36/37/38-20/21/22
R36/37/38:Irritating to eyes, respiratory system and skin.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36-36/37
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.
S36/37:Wear suitable protective clothing and gloves.
RIDADR: 2811
WGK Germany: 3
Hazard Note: Irritant
HazardClass: IRRITANT
Methyl 6-aminonicotinate Specification
6-Aminonicotinic acid methyl ester (CAS NO.36052-24-1) is also named as 3-Pyridinecarboxylic acid, 6-amino-, methyl ester ; 6-Amino-nicotinic acid methyl ester ; Methyl 6-aminonicotinate ; Methyl 2-amino-5-pyridinecarboxylate ; Methyl 2-aminopyridine-5-carboxylate ; Methyl 6-Aminopyridine-3-carboxylate . 6-Aminonicotinic acid methyl ester (CAS NO.36052-24-1) is off-white solid.
What can I do for you?
Get Best Price
