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N-(4-Hydroxyphenyl)glycine

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Name

N-(4-Hydroxyphenyl)glycine

EINECS 204-580-8
CAS No. 122-87-2 Density 1.411 g/cm3
PSA 69.56000 LogP 0.96170
Solubility N/A Melting Point 244 °C (dec.)(lit.)
Formula C8H9NO3 Boiling Point 446.3 °C at 760 mmHg
Molecular Weight 167.164 Flash Point 223.7 °C
Transport Information N/A Appearance white to beige-brown or brown-grey powder
Safety 26-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 122-87-2 (N-(4-HYDROXYPHENYL)GLYCINE) Hazard Symbols IrritantXi
Synonyms

Glycine,N-(p-hydroxyphenyl)- (6CI,7CI,8CI);4-(Carboxymethylamino)phenol;Iconyl;Monazol;N-(4-Hydroxyphenyl)glycine;N-(p-Hydroxyphenyl)glycine;NSC 9267;Photoglycine;p-Hydroxyanilinoacetic acid;p-Hydroxyphenylaminoacetic acid;p-Hydroxyphenylglycine;

 

N-(4-Hydroxyphenyl)glycine Synthetic route

69489-38-9

5-(P-benzyloxyphenyl) hydantoin

901188-62-3

(D)-p-benzyloxyphenylglycine

122-87-2

N-(hydroxyphenyl)glycine

Conditions
ConditionsYield
With acetic acid; Pd-C In conc. NaOH; hydrogen92%
2N-hydrochloric acid

2N-hydrochloric acid

2.22N-sodium hydroxide

2.22N-sodium hydroxide

56405-21-1

DL-p-hydroxyphenylglycine methyl ester

122-87-2

N-(hydroxyphenyl)glycine

Conditions
ConditionsYield
76%
2N-sodium hydroxide

2N-sodium hydroxide

26850-28-2

4-hydroxyphenyl-glycine ethyl ester

122-87-2

N-(hydroxyphenyl)glycine

Conditions
ConditionsYield
With hydrogenchloride66.5%
2706-75-4

sodium glyoxylate

108-95-2

phenol

122-87-2

N-(hydroxyphenyl)glycine

Conditions
ConditionsYield
With ammonium acetate In water50.4%
58645-34-4

potassium glyoxylate

108-95-2

phenol

122-87-2

N-(hydroxyphenyl)glycine

Conditions
ConditionsYield
With ammonium acetate In water33.6%
298-12-4

Glyoxilic acid

108-95-2

phenol

122-87-2

N-(hydroxyphenyl)glycine

Conditions
ConditionsYield
With ammonium acetate In water28.9%
28363-27-1

2-((4-hydroxyphenyl)amino)acetonitrile

122-87-2

N-(hydroxyphenyl)glycine

Conditions
ConditionsYield
With sodium hydroxide
3926-62-3

sodium monochloroacetic acid

123-30-8

4-amino-phenol

122-87-2

N-(hydroxyphenyl)glycine

Conditions
ConditionsYield
With water at 85 - 90℃;
123-30-8

4-amino-phenol

79-11-8

chloroacetic acid

122-87-2

N-(hydroxyphenyl)glycine

Conditions
ConditionsYield
With water
With water; sodium acetate
123-30-8

4-amino-phenol

79-11-8

chloroacetic acid

A

122-87-2

N-(hydroxyphenyl)glycine

B

3987-54-0

(4-hydroxy-phenylimino)-di-acetic acid

Conditions
ConditionsYield
With sodium hydroxide

N-(4-Hydroxyphenyl)glycine Specification

This chemical is called N-(4-Hydroxyphenyl)glycine, and it can also be named as Glycin. The CAS registry number of this chemical is 122-87-2, and its product categories are Glycine Derivatives; Peptide Synthesis; Unnatural Amino Acid Derivatives. This chemical is typically characterized as thin plates of white or silvery powder when it's fresh. It is sparingly soluble in water and most organic solvents. The N-(4-Hydroxyphenyl)glycine is rarely used as a developing agent today, because it is expensive and its manufactured for specialty applications only.

Other characteristics of the N-(4-Hydroxyphenyl)glycine can be summarised as followings: (1)ACD/LogP: -0.13; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -1.37; (4)ACD/LogD (pH 7.4): -3.12; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1.16; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 4; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 38.77 Å2; (13)Index of Refraction: 1.664; (14)Molar Refractivity: 43.94 cm3; (15)Molar Volume: 118.4 cm3; (16)Polarizability: 17.41×10-24cm3; (17)Surface Tension: 70.1 dyne/cm; (18)Density: 1.411 g/cm3; (19)Flash Point: 223.7 °C; (20)Enthalpy of Vaporization: 74.24 kJ/mol; (21)Boiling Point: 446.3 °C at 760 mmHg; (22)Vapour Pressure: 9.49E-09 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following: This chemical is irritating to eyes, respiratory system and skin, so you should wear suitable protective clothing when you use it. In case of contacting with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure: 
1.SMILES: O=C(O)CNc1ccc(O)cc1
2.InChI: InChI=1/C8H9NO3/c10-7-3-1-6(2-4-7)9-5-8(11)12/h1-4,9-10H,5H2,(H,11,12)
3.InChIKey: WRUZLCLJULHLEY-UHFFFAOYAB

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