- 43195-90-01,2-Benzenedicarboxylicacid, 1-cyclohexyl 2-methyl ester
- 4319-77-15-Bromo-4,6-dimethoxypyrimidine ,97%
- 431981-28-11H-Indole-1-acetamide,N-cyclopentyl-3-formyl-
- 431983-71-01H-Indole-1-aceticacid, 3-formyl-2-methyl-, methyl ester
- 4319-85-15-Bromo-4-methoxypyrimidine
- 43200-80-2Zopiclone
- 43200-81-36-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one
- 43200-82-45H-Pyrrolo[3,4-b]pyrazine-5,7(6H)-dione,6-(5-chloro-2-pyridinyl)-
- 43200-96-01-Piperazinecarboxylicacid, 4-methyl-,6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl ester,4-oxide
- 432022-88-34-BROMO-3,5-DIMETHYL-BENZOIC ACID METHYL ESTER
Hot Products
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- 7631-86-9Silicon dioxide
- 302-79-4Tretinoin
- 77-92-9Citric acid
|
Basic Information |
|
Post buying leads |
|
Suppliers |
|
Cas Database |
| Name |
N-Aminomorpholine |
EINECS | 224-347-4 |
| CAS No. | 4319-49-7 | Density | 1.062 g/cm3 |
| PSA | 38.49000 | LogP | -0.16950 |
| Solubility | Miscible with water | Melting Point |
N/A |
| Formula | C4H10N2O | Boiling Point | 168 °C at 760 mmHg |
| Molecular Weight | 102.136 | Flash Point | 58.3 °C |
| Transport Information | UN 1993 3/PG 3 | Appearance | Clear colorless to faintly yellow liquid |
| Safety | 23-16 | Risk Codes | 36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xi
|
| Synonyms |
Morpholine,4-amino- (6CI,7CI,8CI);(Morpholin-4-yl)amine;4-Aminomorpholine;4-Morpholineamine;N-Aminomorpholine;NSC 6825; |
Article Data | 33 |
N-Aminomorpholine Synthetic route
| Conditions | Yield |
|---|---|
| With titanium(III) chloride In water for 1h; Ambient temperature; | 76% |
| With ethanol; sodium | |
| With zinc In acetic acid |
| Conditions | Yield |
|---|---|
| With lithium aluminium tetrahydride In diethyl ether at 0 - 10℃; for 3h; 1) R.T., 1 h 2) reflux, 3 h; | A 31% B 1.0 g |
| With lithium aluminium tetrahydride In diethyl ether at 0 - 10℃; for 3h; 1) R.T., 1 h 2) reflux, 3 h; | A 31% B 31% |
| Conditions | Yield |
|---|---|
| With chloroamine | |
| With potassium hydroxide; hydroxylamine-O-sulfonic acid In water for 0.166667h; Heating; | |
| With ammonium acetate; hydrogenchloride; sodium nitrite In methanol; water |
| Conditions | Yield |
|---|---|
| With sulfuric acid |
| Conditions | Yield |
|---|---|
| With ethanol; hydrazine hydrate |
| Conditions | Yield |
|---|---|
| With titanium(III) chloride; ammonium acetate In water for 1h; Product distribution; Ambient temperature; variation of reaction conditions ( pH<1, pH=9.4 ); | A 3 % Chromat. B 86 % Chromat. |
| With hydrogenchloride; zinc In water for 24h; Product distribution; Ambient temperature; | A 8 % Chromat. B 98 % Chromat. |
| With potassium hydroxide; aluminium In water for 24h; Product distribution; Ambient temperature; | A 43 % Chromat. B 64 % Chromat. |
| Conditions | Yield |
|---|---|
| With acetic acid In acetonitrile Product distribution; Mechanism; |
| Conditions | Yield |
|---|---|
| With acetic acid; zinc |
N-Aminomorpholine Chemical Properties
.jpg)
IUPAC Name: Morpholin-4-amine
Molecular Formula: C4H10N2O
Molecular Weight: 102.14 g/mol
Canonical SMILES: N1(CCOCC1)N
InChI: InChI=1/C4H10N2O/c5-6-1-3-7-4-2-6/h1-5H2
Mol File: 4319-49-7.mol
EINECS: 224-347-4
Classification Code: Mutation data
Product Categories: Variousamine; Aromatic Morpholines; Amines;Morpholines & Thiomorpholines; Morpholines & Thiomorpholines; Building Blocks; Heterocyclic Building Blocks; Morpholines
Water Solubility: miscible
logP(octanol-water): -1.580
XLogP3: -1.1
H-Bond Donor: 1
H-Bond Acceptor: 3
Rotatable Bond Count: 0
Exact Mass: 102.079313
MonoIsotopic Mass: 102.079313
Topological Polar Surface Area: 38.5
Heavy Atom Count: 7
Complexity: 51.7
Index of Refraction: 1.477
Molar Refractivity: 27.17 cm3
Molar Volume: 96.1 cm3
Polarizability: 10.77×10-24cm3
Surface Tension: 36.9 dyne/cm
Density: 1.062 g/cm3
Flash Point: 58.3 °C
Enthalpy of Vaporization: 40.44 kJ/mol
Boiling Point: 168 °C at 760 mmHg
Atmospheric OH Rate Constant: 7.48E-11 cm3/molecule-sec at 25 °C
Vapour Pressure of 4-Morpholinamine (CAS NO.4319-49-7): 1.65 mmHg at 25 °C
N-Aminomorpholine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | oral | > 1gm/kg (1000mg/kg) | Farmaco. Vol. 45, Pg. 223, 1990. |
N-Aminomorpholine Safety Profile
Hazard Codes: 
Xn.
F.
Xi
Risk Statements: 20/21/22-36/37/38
R20/21/22: Harmful by inhalation, in contact with skin and if swallowed.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-23-16
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S23: Do not breathe vapour.
S16: Keep away from sources of ignition.
RIDADR: UN 1993 3/PG 3
WGK Germany: 3
Hazard Note: Harmful
HazardClass: 3
PackingGroup of 4-Morpholinamine (CAS NO.4319-49-7): III
N-Aminomorpholine Specification
4-Morpholinamine (CAS NO.4319-49-7), its Synonyms are Morpholin-4-ylamine ; Morpholine, 4-amino- ; 4-27-00-00623 (Beilstein Handbook Reference) ; 4-Aminomorpholine ; Morpholine, 4-amino- ; N-Aminomorpholine . It is clear colorless to faintly yellow liquid.
What can I do for you?
Get Best Price
