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Cas Database |
| Name |
Naltrexone |
EINECS | 240-649-9 |
| CAS No. | 16590-41-3 | Density | 1.47g/cm3 |
| PSA | 70.00000 | LogP | 1.46330 |
| Solubility | N/A | Melting Point |
168-170° |
| Formula | C20H23 N O4 | Boiling Point | 558.1°C at 760 mmHg |
| Molecular Weight | 341.407 | Flash Point | 291.4°C |
| Transport Information | N/A | Appearance | Crystals from acetone. |
| Safety | Moderately toxic by subcutaneous route. Experimental reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also (−)-MORPHINE and KETONES. | Risk Codes | 11-23/24/25-39/23/24/25 |
| Molecular Structure |
|
Hazard Symbols | F,T |
| Synonyms |
Morphinan-6-one,17-(cyclopropylmethyl)-4,5a-epoxy-3,14-dihydroxy- (8CI); 1-N-Cyclopropylmethyl-7,8-dihydro-14-hydroxynormorphinone;Depotrex; EN 1639; N-Cyclopropylmethylnoroxymorphone; Naltrel; Naltrexone;Nemexin; ReVia; Trexonil; UM 792; Vivitrex; Vivitrol |
Article Data | 46 |
Naltrexone Chemical Properties
Synonyms: 17-(cyclopropylmethyl)-4,5-alpha-epoxy-3,14-dihydroxy-morphinan-6-on;17-(cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-one;5-epoxy-3,14-dihydroxy-17-(cyclopropylmethyl)-(5-alpha)-morphinan-6-on;celupan;en1639;en1939;n-cyclopropylmethyl-14-hydroxydihydromorphinone;
MF: C20H23NO4
MW: 341.4
EINECS: 240-649-9
Naltrexone Toxicity Data With Reference
N-CYCLOPROPYLMETHYLNOROXY-MORPHONE's toxicity information:
1. | sce-hmn:lym 1 g/L | ENMUDM Environmental Mutagenesis. 1 (1979),180. | ||
| 2. | cyt-hmn:lym 1 g/L | ENMUDM Environmental Mutagenesis. 1 (1979),180. | ||
| 3. | sln-dmg-orl 10 g/L/24H | MUREAV Mutation Research. 66 (1979),129. | ||
| 4. | sln-dmg-par 10 g/L | MUREAV Mutation Research. 66 (1979),129. | ||
| 5. | scu-mus LD50:551 mg/kg | ANYAA9 Annals of the New York Academy of Sciences. 281 (1976),321. |
Naltrexone Consensus Reports
Naltrexone Safety Profile
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