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| Name |
Pancreatin |
EINECS | 232-468-9 |
| CAS No. | 8049-47-6 | Density | 1.4-1.52 |
| PSA | 0.00000 | LogP | 0.00000 |
| Solubility | Soluble in water. Insoluble in alcohol and ether. | Melting Point |
N/A |
| Formula | N/A | Boiling Point | N/A |
| Molecular Weight | N/A | Flash Point | N/A |
| Transport Information | N/A | Appearance | cream powder |
| Safety | 22-24-26-36-37/39 | Risk Codes | 36/37/38-42-42/43 |
| Molecular Structure |
|
Hazard Symbols |
 Xn
|
| Synonyms |
Beef viokase;Diastase vera;HSDB 1976;llozyme;Intrazyme;Norzyme;Pancreatic enzymes;Pancreatic extract;Pancrelipase;Pancrex-V;Pankreon;Pankrotanon;Panteric;UNII-FQ3DRG0N5K;Viobin;Viokase;Zypanar; |
Pancreatin Chemical Properties
Product Name: Pancreatin
Synonyms of Pancreatin (CAS NO.8049-47-6): Beef viokase ; Diastase vera ; EINECS 232-468-9 ; HSDB 1976 ; Ilozyme ; Intrazyme ; Norzyme ; Pancreatic enzymes ; Pancreatic extract ; Pancrelipase ; Pancrex-V ; Pankreon ; Pankrotanon ; Panteric ; UNII-FQ3DRG0N5K ; Viobin ; Viokase ; Zypanar
CAS NO: 8049-47-6
Classification Code: Drug / Therapeutic Agent ; Enzyme [digestant adjunct] ; Gastrointestinal agents ; TSCA Flag XU [Exempt from reporting under the Inventory Update Rule]
Storage temp.: −20°C
Form: powder
Merck: 13,7075
Stability: Stable. Incompatible with alcohols, strong acids.
Pancreatin Uses
Pancreatin (CAS NO.8049-47-6) can be used for the goods donated for the lack of pancreatic indigestion. Also for the leather and textile industries, mainly for hair removal method.
Pancreatin Production
Pancreatin (CAS NO.8049-47-6) is produced by activation, extraction, precipitation, degreasing, drying, crushing of milled pig pancreas.
Pancreatin Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 2100mg/kg (2100mg/kg) | SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975. |
| mouse | LD50 | oral | > 10gm/kg (10000mg/kg) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975. | |
| mouse | LD50 | subcutaneous | 3870mg/kg (3870mg/kg) | SKIN AND APPENDAGES (SKIN): HAIR: OTHER | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975. |
| rat | LD50 | intraperitoneal | 2550mg/kg (2550mg/kg) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975. | |
| rat | LD50 | oral | > 10gm/kg (10000mg/kg) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975. | |
| rat | LD50 | subcutaneous | > 5gm/kg (5000mg/kg) | Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975. |
Pancreatin Consensus Reports
Reported in EPA TSCA Inventory.
Pancreatin Safety Profile
Hazard Codes: 
Xn
Risk Statements: 36/37/38-42/43
R36/37/38: Irritating to eyes, respiratory system and skin.
R42/43: May cause sensitization by inhalation and skin contact.
Safety Statements: 22-24-26-36-37/39
S22: Do not breathe dust.
S24: Avoid contact with skin.
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36: Wear suitable protective clothing.
S37/39: Wear suitable gloves and eye/face protection.
WGK Germany: 1
RTECS: RT9033000
F: 3-10
HS Code: 35079090
Moderately toxic by subcutaneous and intraperitoneal routes.
Pancreatin Specification
Precautions of Pancreatin (CAS NO.8049-47-6): Do not ingest. Do not breathe dust. Keep away from heat. Keep away from sources of ignition. If ingested, seek medical advice immediately and show the container or the label. Empty containers pose a fire risk, evaporate the residue under a fume hood. Ground all equipment containing material.
Storage of Pancreatin (CAS NO.8049-47-6): Keep container tightly closed. Keep in a cool, well-ventilated place. Keep in a cool place. Keep container dry. Ground all equipment containing material. Combustible materials should be stored away from extreme heat and away from strong oxidizing agents.
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