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Name	Pirenzepine hydrochloride	EINECS	249-907-5
CAS No.	29868-97-1	Density	g/cm³
PSA	74.23000	LogP	2.80740
Solubility	50 mg/mL in water	Melting Point	248-250 °C
Formula	C₁₉H₂₁N₅O₂^.2(HCl)	Boiling Point	541.7 °C at 760 mmHg
Molecular Weight	424.33	Flash Point	281.4 °C
Transport Information	N/A	Appearance	white powder
Safety		Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	6H-Pyrido[2,3-b][1,4]benzodiazepin-6-one,5,11-dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-, dihydrochloride (8CI,9CI);5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyrido[2,3-b][1,4]benzodiazepin-6-onedihydrochloride;Duogastral;Durapirenz;Gasteril;Gastricur;Gastrozepin;L-S 519;LS 519Cl2;LS 59Cl2;Leblon;Maghen;Pirenzepine dihydrochloride;Pirenzepinehydrochloride;Renzepin;Tabe;Ulcosan;Ulcuforton;

Pirenzepine hydrochloride Chemical Properties

IUPAC Name: Pirenzepine hydrochloride
CAS: 29868-97-1
Formula: C₁₉H₂₃C_l2N₅O₂
Molecular Weight: 424.32
Molecular Structure of Pirenzepine hydrochloride (29868-97-1):

Flash Point: 281.4 °C
Melting Point: 248-250°C
Boiling Point: 541.7 °C at 760 mmHg
Appearance: white powder
Enthalpy of Vaporization: 81.97 kJ/mol
Vapour Pressure: 8.44E-12 mmHg at 25°C
Water Solubility: 50(mg/mL) at 25°C
Product Categories: all inhibitors;inhibitor;intermediates & fine chemicals;pharmaceuticals;acetylcholine receptor.

Pirenzepine hydrochloride Toxicity Data With Reference

1.	orl-rat LD50:5 g/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),328.
2.	ipr-rat LD50:440 mg/kg	YAKUD5 Gekkan Yakuji. Pharmaceuticals Monthly. 23 (1981),1999.
3.	scu-rat LD50:3 g/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
4.	ivn-rat LD50:92 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
5.	orl-mus LD50:2600 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 11 (1980),328.
6.	ipr-mus LD50:407 mg/kg	DRUGAY Drugs. International Journal of Current Therapeutics and Applied Pharmacology Reviews. 6 (1982),645.
7.	scu-mus LD50:2100 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
8.	ivn-mus LD50:96 mg/kg	IYKEDH Iyakuhin Kenkyu. Study of Medical Supplies. 19 (1988),735.
9.	orl-rbt LD50:3000 mg/kg	OYYAA2 Oyo Yakuri. Pharmacometrics. 9 (1975),377.

Pirenzepine hydrochloride Safety Profile

Poison by intravenous route. Moderately toxic by ingestion and intraperitoneal route. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NO_x and HCl. See also DIAZEPAM.
Safety Information about Pirenzepine hydrochloride (29868-97-1):
WGK Germany: 2
RTECS: UU7883000

Pirenzepine hydrochloride Specification

The chemical synonyms of Pirenzepine hydrochloride (29868-97-1) are 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6h-pyrido-[2,3-b][1,4] benzodiazepin-6-one dihydrobromide ; 5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6h-pyrido-[2,3-b] [1,4]benzodiazepin-6-one dihydrochloride ; 5,11-Dihydro-11-[(4-methylpiperazin-1-yl)acetyl]-6h-pyrido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride ; Pirenzepine dihydrochloride ; Pirenzepine hcl hydrate ; Pirenzepine hydrochloride .It belongs to acid-suppressing drugs.It can be used in a variety of clinical acid-related disorders, such as: duodenal ulcer, gastric ulcer, stomach - esophageal reflux disease, high-acid gastritis, stress ulcer, acute gastric mucosal bleeding, gastrin tumors and so on.

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