2-Methylcyclohexylamine, (1S,2S)-

Base Information

Chemical Name:2-Methylcyclohexylamine, (1S,2S)-
CAS No.:29569-76-4
Molecular Formula:C7H15N
Molecular Weight:113.203
Hs Code.:
UNII:S0SG38192N
Nikkaji Number:J1.315.456B
Wikidata:Q27288411
Mol file:29569-76-4.mol

Synonyms:29569-76-4;(1S,2S)-2-methylcyclohexan-1-amine;Cyclohexanamine, 2-methyl-, (1S,2S)-;2-Methylcyclohexylamine, (1S,2S)-;2-Methylcyclohexylamine, trans-(+)-;Cyclohexylamine, 2-methyl-, trans-(+)-;Cyclohexanamine, 2-methyl-, (1S-trans)-;UNII-S0SG38192N;(1S,2S)-2-Methylcyclohexanamine;S0SG38192N;(1S,2S)-2-Methyl-cyclohexylamine;SCHEMBL735479;(1S,2S)-2-methylcyclohexylamine;MFCD19237988;Q27288411

Suppliers and Price of 2-Methylcyclohexylamine, (1S,2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Methylcyclohexylamine, (1S,2S)-

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:113.120449483
Heavy Atom Count:8
Complexity:70.8

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1CCCCC1N
Isomeric SMILES:C[C@H]1CCCC[C@@H]1N

Technology Process of 2-Methylcyclohexylamine, (1S,2S)-

There total 9 articles about 2-Methylcyclohexylamine, (1S,2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 68820-12-2
cyclohexyl-N-tosyl aziridine

: 75-16-1
methylmagnesium bromide

: 931-11-3
(1R,2R)-2-methyl-1-cyclohexylamine

: 29569-76-4
(1S,2S)-2-methyl-1-cyclohexylamine

Guidance literature:: cyclohexyl-N-tosyl aziridine; methylmagnesium bromide; D-phenylglycine-derived Shiff base Cu-catayst; In tetrahydrofuran; toluene; at 0 ℃; for 1h;

With ammonia; sodium; at -78 ℃; Further stages. Title compound not separated from byproducts.;
DOI:10.1021/ol990650b

Reference yield:

: 583-60-8
2-Methylcyclohexanone

: 931-11-3
(1R,2R)-2-methyl-1-cyclohexylamine

: 79389-37-0
(1R,2S)-(+)-cis-2-Methyl-cyclohexanamin

: 79389-36-9
(1S,2R)-(-)-cis-2-Methyl-cyclohexanamin

: 29569-76-4
(1S,2S)-2-methyl-1-cyclohexylamine

Guidance literature:: 2-Methylcyclohexanone; With [((R)-tol-binap)RuCl₂(DMF)x]; ammonium formate; In methanol; at 85 ℃; for 20h;

With hydrogenchloride; In ethanol; for 1h; Title compound not separated from byproducts; Heating;
DOI:10.1002/anie.200352503

Reference yield:

: 583-60-8
2-Methylcyclohexanone

: 931-11-3
(1R,2R)-2-methyl-1-cyclohexylamine

: 29569-76-4
(1S,2S)-2-methyl-1-cyclohexylamine

Guidance literature:: 2-Methylcyclohexanone; With potassium hydroxide; Noyori's Ru catalyst; hydrogen; In isopropyl alcohol; at 20 ℃; for 72h; under 3361.46 Torr;

With diphenylphosphoranyl azide; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; at 20 ℃; for 18h;

With water; triphenylphosphine; In tetrahydrofuran; for 16h; Title compound not separated from byproducts; Heating;
DOI:10.3390/90600405