2-Phenylbenzoselenazole

Base Information

• Chemical Name: 2-Phenylbenzoselenazole
• CAS No.: 32586-68-8
• Molecular Formula: C13H9NSe
• Molecular Weight: 258.181
• Mol file: 32586-68-8.mol

Synonyms:2-Phenylbenzoselenazol;2-phenyl-benzoselenazole;2-phenylbenzo-1,3-selenazole;2-phenyl-1,3-benzoselenazole;2-Phenyl-benzoselenazol;

Chemical Property of 2-Phenylbenzoselenazole

Chemical Property:

• Melting Point: 112 - 114 °C
• Boiling Point: 220-230 °C(Press: 28 Torr)
• PKA: 3.96±0.11(Predicted)
• PSA: 12.89000
• LogP: 2.95880

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Phenylbenzoselenazole

There total 21 articles about 2-Phenylbenzoselenazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-(4-tolylthio)-1,3-benzoselenazole + phenylmagnesium bromide → 2-phenylbenzo[d][1,3]selenazole (32586-68-8)

Guidance literature:

With 1,2-bis(diphenylphosphino)ethane nickel(II) chloride; In tetrahydrofuran; at 20 ℃; for 14h;

DOI:10.1021/jo7013164

Reference yield: 83.0%

bis(2-aminophenyl)diselenide (63870-44-0) + benzaldehyde (100-52-7) → 2-phenylbenzo[d][1,3]selenazole (32586-68-8)

Guidance literature:

With sodium metabisulfite; In dimethyl sulfoxide; at 120 ℃; for 48h; Inert atmosphere; Microwave irradiation;

DOI:10.1016/j.tet.2012.11.091

Reference yield: 83.0%

phenylacetic acid (103-82-2) + 2-iodophenylamine (615-43-0) → 2-phenylbenzo[d][1,3]selenazole (32586-68-8)

Guidance literature:

With selenium; potassium hydroxide; copper(I) bromide; In dimethyl sulfoxide; at 120 ℃; for 18h; Reagent/catalyst; Solvent; Mechanism; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.tetlet.2018.06.027

upstream raw materials:

N-phenyl benzoyl amide

benzylidene phenylamine

zinc 2-aminobenzeneselenolate

benzoyl chloride

Downstream raw materials:

(2-phenylbenzo-1,3-selenazole)trifluoroboron

Refernces

• 1、 Radatz, Catia Schwartz,Coelho, Felipe Lange,Gil, Eduarda Sangiogo,da Silveira Santos, Fabiano,Schneider, Juliana Maria Forain Miolo,Gon?alves, Paulo Fernando Bruno,Rodembusch, Fabiano Severo,Schneider, Paulo Henrique. "Ground and excited-state properties of 1,3-benzoselenazole derivatives: A combined theoretical and experimental photophysical investigation". . . Retrieved 2020/02/06.
• 2、 Gu, Ren,Wang, Xin,Yang, Zhao,Han, Shiqing. "Se-mediated one-pot synthesis of 2-substituted benzoselenazole derivatives from 2 to iodoanilines and arylacetic acids/arylmethyl chlorides". . p. 2835 - 2838. Retrieved 2018/06/25.