4-fluoro-N-(4-methylphenyl)benzenesulfonamide

Base Information

Chemical Name:4-fluoro-N-(4-methylphenyl)benzenesulfonamide
CAS No.:339-41-3
Molecular Formula:C13H12FNO2S
Molecular Weight:265.308
Hs Code.:
DSSTox Substance ID:DTXSID401253494
ChEMBL ID:CHEMBL182491

Synonyms:4-fluoro-N-(4-methylphenyl)benzenesulfonamide;339-41-3;4-Fluoro-N-(p-tolyl)benzenesulfonamide;Cambridge id 5349350;CHEMBL182491;SCHEMBL3367872;DTXSID401253494;MFCD00447247;STK049090;AKOS002376733;AB00005663-01;AB00005663-02;4-fluoro-N-(4-methylphenyl)-1-benzenesulfonamide;AE-848/06093048;SR-01000206233;SR-01000206233-1

Suppliers and Price of 4-fluoro-N-(4-methylphenyl)benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-fluoro-N-(4-methylphenyl)benzenesulfonamide

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:265.05727796
Heavy Atom Count:18
Complexity:350

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)NS(=O)(=O)C2=CC=C(C=C2)F

Technology Process of 4-fluoro-N-(4-methylphenyl)benzenesulfonamide

There total 4 articles about 4-fluoro-N-(4-methylphenyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 349-88-2
4-Fluorobenzenesulfonyl chloride

: 106-49-0,12221-03-3
p-toluidine

: 339-41-3
4-fluoro-N-(p-tolyl)benzenesulfonamide

Guidance literature:: In pyridine; ethyl acetate;

Reference yield: 50.0%

: 99-99-0
1-methyl-4-nitrobenzene

: 824-80-6
sodium 4-fluorobenzenesulfinate

: 339-41-3
4-fluoro-N-(p-tolyl)benzenesulfonamide

Guidance literature:: With copper(l) chloride; In 1-methyl-pyrrolidin-2-one; water; at 120 ℃; for 40h; Inert atmosphere;
DOI:10.3390/molecules24071407

Reference yield:

: 623-11-0
1-methyl-4-nitrosobenzene

: 371-40-4
4-fluoroaniline

: 339-41-3
4-fluoro-N-(p-tolyl)benzenesulfonamide

Guidance literature:: 4-fluoroaniline; With hydrogenchloride; sodium nitrite; In water; at 0 ℃;

With sodium tetrafluoroborate; In water;

1-methyl-4-nitrosobenzene; With cyclohexa-1,4-diene; 1,4-diazabicyclo [2.2.2] octane-1,4-diium-1,4-disulfinate; In acetonitrile; at 60 ℃; for 16h; Sealed tube; Inert atmosphere;
DOI:10.1002/cjoc.202000053