1H-Indole-3-acetyl chloride, 1-[(4-chlorophenyl)methyl]-a-oxo-

Base Information

Chemical Name:1H-Indole-3-acetyl chloride, 1-[(4-chlorophenyl)methyl]-a-oxo-
CAS No.:348111-64-8
Molecular Formula:C17H11Cl2NO2
Molecular Weight:332.186
Hs Code.:
Mol file:348111-64-8.mol

Synonyms:[1-(4-Chloro-benzyl)-1H-indol-3-yl]-oxo-acetyl chloride;2-(1-(4-chlorobenzyl)-1H-indol-3-yl)-2-oxo-acetyl chloride;

Suppliers and Price of 1H-Indole-3-acetyl chloride, 1-[(4-chlorophenyl)methyl]-a-oxo-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1H-Indole-3-acetyl chloride, 1-[(4-chlorophenyl)methyl]-a-oxo-

Chemical Property:

PSA：39.07000
LogP:4.29110

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1H-Indole-3-acetyl chloride, 1-[(4-chlorophenyl)methyl]-a-oxo-

There total 4 articles about 1H-Indole-3-acetyl chloride, 1-[(4-chlorophenyl)methyl]-a-oxo- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 79-37-8
oxalyl dichloride

: 85607-00-7
1-(4'-chlorobenzyl)-indole

: 348111-64-8
2-[1-(4-chlorobenzyl)-1H-indol-3-yl]-2-oxoacetyl chloride

Guidance literature:: In various solvent(s); at 5 ℃; for 3.5h;
DOI:10.1002/1099-0690(200110)2001:20<3843::AID-EJOC3843>3.0.CO;2-P

Reference yield:

: 120-72-9
indole

: 348111-64-8
2-[1-(4-chlorobenzyl)-1H-indol-3-yl]-2-oxoacetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: 80percent NaH / dimethylformamide / 70 °C

1.2: 97 percent / dimethylformamide / 3 h / 20 °C

2.1: 90 percent / various solvent(s) / 3.5 h / 5 °C

With 80percent NaH; In N,N-dimethyl-formamide;
DOI:10.1002/1099-0690(200110)2001:20<3843::AID-EJOC3843>3.0.CO;2-P

Reference yield:

: 104-83-6
1-Chloro-4-(chloromethyl)benzene

: 348111-64-8
2-[1-(4-chlorobenzyl)-1H-indol-3-yl]-2-oxoacetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: 80percent NaH / dimethylformamide / 70 °C

1.2: 97 percent / dimethylformamide / 3 h / 20 °C

2.1: 90 percent / various solvent(s) / 3.5 h / 5 °C

With 80percent NaH; In N,N-dimethyl-formamide;
DOI:10.1002/1099-0690(200110)2001:20<3843::AID-EJOC3843>3.0.CO;2-P