1-Methoxy-4-[(E)-3-phenylallyl]benzene

Base Information

• Chemical Name: 1-Methoxy-4-[(E)-3-phenylallyl]benzene
• CAS No.: 35856-80-5
• Molecular Formula: C₁₆H₁₆O
• Molecular Weight: 224.302
• Mol file: 35856-80-5.mol

Synonyms:(E)-1-(3-(4-methoxyphenyl)prop-1-enyl)benzene;1-methoxy-4-[(E)-3-phenyl-2-propenyl]benzene;1-methoxy-4-[(2E)-3-phenyl-2-propen-1-yl]benzene;(E)-1-phenyl-3-(4-methoxyphenyl)-1-propene;(E)-1-methoxy-4-(3-phenyl-2-propen-1-yl)benzene;1-methoxy-4-[(E)-3-phenylprop-2-en-1-yl]benzene;

Chemical Property of 1-Methoxy-4-[(E)-3-phenylallyl]benzene

Chemical Property:

• Melting Point: 33 - 34 °C
• PSA: 9.23000
• LogP: 3.95110

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Methoxy-4-[(E)-3-phenylallyl]benzene

There total 168 articles about 1-Methoxy-4-[(E)-3-phenylallyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-methoxyphenylzinc chloride (93296-09-4) + (2E)-3-phenyl-2-propen-1-ol (4407-36-7) → (1E)-3-(4-methoxyphenyl)-1-phenylpropene (20442-73-3,35856-80-5)

Guidance literature:

(2E)-3-phenyl-2-propen-1-ol; With nickel(II) triflate; 1,2-bis-(diphenylphosphino)ethane; methylzinc chloride; In tetrahydrofuran; at 20 ℃; for 0.0833333h; Inert atmosphere; Schlenk technique;

4-methoxyphenylzinc chloride; In dibutyl ether; toluene; at 120 ℃; for 24h; regioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.joc.6b02564

Reference yield: 98.0%

Cinnamyl acetate (21040-45-9) + 4-methoxyphenylboronic acid (5720-07-0) → (1E)-3-(4-methoxyphenyl)-1-phenylpropene (20442-73-3,35856-80-5)

Guidance literature:

With potassium fluoride; In methanol; at 70 ℃; for 3h;

DOI:10.1002/anie.201103799

Reference yield: 96.0%

methoxybenzene (100-66-3) + (2E)-3-phenyl-2-propen-1-ol (4407-36-7) → (1E)-3-(4-methoxyphenyl)-1-phenylpropene (20442-73-3,35856-80-5)

Guidance literature:

With [Cp*Ir(SnCl₃)2{SnCl₂(H₂O)2}]; In dichloromethane; at 20 ℃; regioselective reaction; Kinetics; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.tet.2012.10.086

upstream raw materials:

(E)-3-Phenyl-acrylic acid (E)-1-(4-methoxy-phenyl)-3-phenyl-allyl ester

(E)-cinnamyl(tributyl)tin

methoxybenzene

4-methoxyphenyl magnesium bromide

Downstream raw materials:

4'-methoxychalcone

3-(4-methoxyphenyl)-1-phenylprop-2-en-1-one

1‐methoxy‐4‐(3‐phenylpropyl)benzene