2-(Trifluoromethyl)biphenyl

Base Information

Chemical Name:2-(Trifluoromethyl)biphenyl
CAS No.:362-59-4
Molecular Formula:C13H9F3
Molecular Weight:222.21
Hs Code.:
DSSTox Substance ID:DTXSID30468417
Nikkaji Number:J895.619G
Mol file:362-59-4.mol

Synonyms:2-(Trifluoromethyl)biphenyl;362-59-4;1-phenyl-2-(trifluoromethyl)benzene;2-(TRIFLUOROMETHYL)-1,1'-BIPHENYL;2-trifluoromethyl-biphenyl;SCHEMBL163729;DTXSID30468417;LRYZJEXQHWCLJY-UHFFFAOYSA-N;MFCD14525536;AKOS005257990;FT-0686363

Suppliers and Price of 2-(Trifluoromethyl)biphenyl

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 2-(Trifluoromethyl)biphenyl

Chemical Property:

XLogP3:4.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:222.06563477
Heavy Atom Count:16
Complexity:216

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC=CC=C2C(F)(F)F

Technology Process of 2-(Trifluoromethyl)biphenyl

There total 4 articles about 2-(Trifluoromethyl)biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 444-29-1
2-iodo(trifluoromethyl)benzene

: 595-90-4
tetraphenyltin(IV)

: 92-52-4,1594-86-1
biphenyl

: 362-59-4
2-trifluoromethyl-biphenyl

Guidance literature:: With lithium chloride; In N,N-dimethyl-formamide; at 140 ℃; for 12h; Inert atmosphere;
DOI:10.1021/acs.joc.6b01648

Reference yield: 23.0%

: 108-86-1,52753-63-6
bromobenzene

: 392-83-6
o-trifluoromethylphenyl bromide

: 92-52-4,1594-86-1
biphenyl

: 362-59-4
2-trifluoromethyl-biphenyl

Guidance literature:: bromobenzene; With magnesium; In diethyl ether;

o-trifluoromethylphenyl bromide; In diethyl ether; for 3h; Reflux;
DOI:10.1039/b919246h

Reference yield:

: 73475-34-0
[2-(trifluoromethyl)phenyl](diphenyl)methanol

: 108-90-7
chlorobenzene

: 119-61-9
benzophenone

: 92-52-4,1594-86-1
biphenyl

: 727-99-1
2-trifluoromethylbenzophenone

: 362-59-4
2-trifluoromethyl-biphenyl

Guidance literature:: With palladium diacetate; caesium carbonate; tricyclohexylphosphine; In o-xylene; for 2h; Title compound not separated from byproducts; Heating;
DOI:10.1021/jo0344034