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1S,3R,4S)-(+)-4-azido-3-[(tert-butoxycarbonyl)aMino]cyclohexanecarboxylic acid ethyl ester

Base Information Edit
  • Chemical Name:1S,3R,4S)-(+)-4-azido-3-[(tert-butoxycarbonyl)aMino]cyclohexanecarboxylic acid ethyl ester
  • CAS No.:365997-34-8
  • Molecular Formula:C14H24N4O4
  • Molecular Weight:312.369
  • Hs Code.:
  • Mol file:365997-34-8.mol
1S,3R,4S)-(+)-4-azido-3-[(tert-butoxycarbonyl)aMino]cyclohexanecarboxylic acid ethyl ester

Synonyms:D-1310;Cyclohexanecarboxylic acid,4-azido-3-[[(1,1-dimethylethoxy)carbonyl]amino]-,ethyl ester,(1S,3R,4S);

Suppliers and Price of 1S,3R,4S)-(+)-4-azido-3-[(tert-butoxycarbonyl)aMino]cyclohexanecarboxylic acid ethyl ester
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Chemenu
  • ethyl(1S,3R,4S)-4-azido-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate 97%
  • 5g
  • $ 1485.00
  • Chemenu
  • ethyl(1S,3R,4S)-4-azido-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate 97%
  • 1g
  • $ 495.00
  • ACHEMBLOCK
  • 1S,3R,4S)-(+)-4-azido-3-[(tert-butoxycarbonyl)amino]cyclohexanecarboxylicacidethylester 97%
  • 250MG
  • $ 225.00
Total 15 raw suppliers
Chemical Property of 1S,3R,4S)-(+)-4-azido-3-[(tert-butoxycarbonyl)aMino]cyclohexanecarboxylic acid ethyl ester Edit
Chemical Property:
  • PSA:117.87000 
  • LogP:2.57896 
  • Storage Temp.:Refrigerator 
  • Solubility.:Dichloromethane; Ethyl Acetate 
Purity/Quality:

97% *data from raw suppliers

ethyl(1S,3R,4S)-4-azido-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate 97% *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Uses Ethyl (1S,3R,4S)-4-Azido-3-(tert-butoxycarbonylamino)cyclohexane-1-carboxylate is an intermediate in the synthesis of Edoxaban-d6 (E555522), the isotope labelled analog of Edoxaban (E555520); an anticoagulant drug which acts as a direct factor Xa inhibitor.
Technology Process of 1S,3R,4S)-(+)-4-azido-3-[(tert-butoxycarbonyl)aMino]cyclohexanecarboxylic acid ethyl ester

There total 11 articles about 1S,3R,4S)-(+)-4-azido-3-[(tert-butoxycarbonyl)aMino]cyclohexanecarboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With sodium azide; N-benzyl-N,N,N-triethylammonium chloride; In N,N-dimethyl-formamide; at 55 - 60 ℃; for 48h;
Guidance literature:
ethyl (1S,3R,4R)-3-(tert-butoxycarbonylamino)-4-hydroxycyclohexane-1-carboxylate; With methanesulfonyl chloride; triethylamine; In dichloromethane; at -15 - 20 ℃; for 4.33333h;
With hydrogenchloride; In dichloromethane; water; at 0 ℃;
With sodium azide; In DMF (N,N-dimethyl-formamide); at 67 - 75 ℃; for 16h;
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