m-Trimethylsilyltoluene

Base Information

• Chemical Name: m-Trimethylsilyltoluene
• CAS No.: 3728-44-7
• Molecular Formula: C10H16Si
• Molecular Weight: 164.323
• DSSTox Substance ID: DTXSID80446346
• Nikkaji Number: J483.901C
• Wikidata: Q82264971
• Mol file: 3728-44-7.mol

Synonyms:3728-44-7;m-Trimethylsilyltoluene;trimethyl-m-tolyl-silane;Silane, trimethyl(3-methylphenyl)-;TRIMETHYL(M-TOLYL)SILANE;m-Tolyltrimethylsilane;3-trimethylsilyltoluene;DTXSID80446346;OVMFTFDFVZRFJD-UHFFFAOYSA-N;1-Methyl-3-Trimethylsilyl-Benzene

Chemical Property of m-Trimethylsilyltoluene

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 164.102127045
• Heavy Atom Count: 11
• Complexity: 123

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)[Si](C)(C)C

Technology Process of m-Trimethylsilyltoluene

There total 21 articles about m-Trimethylsilyltoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

chloro-trimethyl-silane (75-77-4) + 1-chloro-3-methylbenzene (108-41-8) → 3-(trimethylsilyl)toluene (3728-44-7)

Guidance literature:

1-chloro-3-methylbenzene; With magnesium; ethylene dibromide; In tetrahydrofuran; for 4h; Heating;

chloro-trimethyl-silane; In tetrahydrofuran;

DOI:10.1021/jm021107v

Reference yield: 90.0%

chloro-trimethyl-silane (75-77-4) + meta-bromotoluene (591-17-3) → 3-(trimethylsilyl)toluene (3728-44-7)

Guidance literature:

meta-bromotoluene; With iodine; magnesium; In tetrahydrofuran; at 20 ℃; for 1h; Reflux;

chloro-trimethyl-silane; In tetrahydrofuran; at 20 ℃; for 18h;

DOI:10.1021/jacs.7b06668

Reference yield: 89.0%

1-chloro-3-methylbenzene (108-41-8) + ethylene dibromide (106-93-4) → 3-(trimethylsilyl)toluene (3728-44-7)

Guidance literature:

With chloro-trimethyl-silane; sodium hydrogencarbonate; magnesium; In tetrahydrofuran; dichloromethane;

upstream raw materials:

chloro-trimethyl-silane

1-chloro-3-methylbenzene

meta-bromotoluene

m-tolyllithium

Downstream raw materials:

(3-dibromomethyl-phenyl)-trimethyl-silane

1-bromomethyl-3-trimethylsilyl-benzene

Trimethyl-silyl-<3-methyl-benzol-sulfonat>

3-Methyl-cyclohexyl-trimethyl-silan