Acetamide, N-(phenyl-1-piperidinylmethyl)-

Base Information

• Chemical Name: Acetamide, N-(phenyl-1-piperidinylmethyl)-
• CAS No.: 37733-79-2
• Molecular Formula: C₁₄H₂₀N₂O
• Molecular Weight: 232.326
• DSSTox Substance ID: DTXSID00433637
• Nikkaji Number: J1.171.286J
• Mol file: 37733-79-2.mol

Synonyms:37733-79-2;Acetamide, N-(phenyl-1-piperidinylmethyl)-;piperidinobenzyl acetamide;DTXSID00433637;N-(alpha-Piperidinobenzyl)acetamide

Chemical Property of Acetamide, N-(phenyl-1-piperidinylmethyl)-

Chemical Property:

• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 232.157563266
• Heavy Atom Count: 17
• Complexity: 243

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)NC(C1=CC=CC=C1)N2CCCCC2

Technology Process of Acetamide, N-(phenyl-1-piperidinylmethyl)-

There total 2 articles about Acetamide, N-(phenyl-1-piperidinylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

piperidine (110-89-4) + acetamide (60-35-5) + benzaldehyde (100-52-7) → N-[1-piperidinobenzyl]acetamide (37733-79-2)

Guidance literature:

at 20 ℃; for 168h;

Reference yield:

→ N-[1-piperidinobenzyl]acetamide (37733-79-2)

Guidance literature:

durch kat. Hydrogenolyse;

Reference yield:

N-[1-piperidinobenzyl]acetamide (37733-79-2) + uranyl nirate hexahydrate + dihydrogen peroxide (7722-84-1) → UO(peroxo)(piperidinobenzyl acetamide)(NO3)2

Guidance literature:

With KOH; In methanol; byproducts: H2O; UO2(NO3)2*6H2O dissolved in MeOH; equimolar amts. of soln. of ligand in MeOH added; KOH added; soln. refluxed for 15 min; 30% H2O2 added dropwise; mixt. refluxed for 1 h; cooled; filtered; washed (MeOH, ether); dried (vac.); elem. anal.;

DOI:10.1134/S003602361208013X

upstream raw materials:

piperidine

acetamide

benzaldehyde

Downstream raw materials:

Mn(C₁₄H₂₀N₂O)2(NO₃)2

Zn(C₁₄H₂₀N₂O)Br₂

Co(C₁₄H₂₀N₂O)Br₂

Ni(C₁₄H₂₀N₂O)2Br₂