4-[(Trimethylsilyl)amino]butyric acid trimethylsilyl ester

Base Information

• Chemical Name: 4-[(Trimethylsilyl)amino]butyric acid trimethylsilyl ester
• CAS No.: 39538-11-9
• Molecular Formula: C10H25NO2Si2
• Molecular Weight: 247.48200
• Mol file: 39538-11-9.mol

Synonyms:N,O-Bis-(trimethylsilyl)-4-aminobuttersaeure;N-Trimethylsilyl-4-aminobutyric acid trimethylsilyl ester;4-[(Trimethylsilyl)amino]butyric acid trimethylsilyl ester;N,O-bis(trimethylsilyl)-4-aminobutyric acid;Butanoic acid,4-[(trimethylsilyl)amino]-,trimethylsilyl ester;

Chemical Property of 4-[(Trimethylsilyl)amino]butyric acid trimethylsilyl ester

Chemical Property:

• PSA: 38.33000
• LogP: 2.96010

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-[(Trimethylsilyl)amino]butyric acid trimethylsilyl ester

There total 3 articles about 4-[(Trimethylsilyl)amino]butyric acid trimethylsilyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

chloro-trimethyl-silane (75-77-4) + 4-amino-n-butyric acid (56-12-2) → N,O-bis(trimethylsilyl)-4-aminobutyric acid (39538-11-9)

Guidance literature:

With triethylamine; In benzene; Ambient temperature;

DOI:10.1021/jm00376a005

Reference yield:

toluene-4-sulfonic acid ; 4-amino-butyric acid-salt (71890-28-3) + 1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) → N,O-bis(trimethylsilyl)-4-aminobutyric acid (39538-11-9)

Guidance literature:

In dichloromethane; for 0.5h; Ambient temperature;

DOI:10.1055/s-1982-30060

Reference yield:

→ N,O-bis(trimethylsilyl)-4-aminobutyric acid (39538-11-9)

Guidance literature:

4-Aminobuttersaeure, Bis-TMS-trifluoracetamid;

DOI:10.1016/S0021-9673(00)93539-8

upstream raw materials:

chloro-trimethyl-silane

4-amino-n-butyric acid

toluene-4-sulfonic acid ; 4-amino-butyric acid-salt

1,1,1,3,3,3-hexamethyl-disilazane

Downstream raw materials:

4-(N'-phenyl-ureido)-butyric acid

4-10-methylpteroyl)amino>butyric acid