(R)-(+)-1-Phenyl-1-butanol

Base Information Edit

Chemical Name:(R)-(+)-1-Phenyl-1-butanol
CAS No.:22144-60-1
Molecular Formula:C10H14 O
Molecular Weight:150.221
Hs Code.:2906299090
UNII:4L6AR026JN
DSSTox Substance ID:DTXSID001030850
Nikkaji Number:J56.813I
Wikidata:Q27259965
Mol file:22144-60-1.mol

Synonyms:(R)-(+)-1-Phenyl-1-butanol;22144-60-1;(1R)-1-phenylbutan-1-ol;1-Phenylbutanol, (+)-;(r)-1-phenylbutan-1-ol;(+)-1-phenylbutanol;UNII-4L6AR026JN;4L6AR026JN;(r)-(+)-1-phenyl-butan-1-ol;Benzenemethanol, .alpha.-propyl-, (R)-;(R)-1-Phenyl-1-butanol;(R)-1-phenyl-butane-1-ol;SCHEMBL540695;1-PHENYLBUTANOL, (R)-;HQRWWHIETAKIMO-SNVBAGLBSA-N;(R)-(+)-1-Phenylbutan-1-ol;DTXSID001030850;(R)-1-PHENYLBUTANE-1-OL;(+)-1-PHENYL-1-BUTANOL;MFCD00004575;(R)-1-Phenyl-1-butanol, ee 99%;AKOS016346857;(R)-(+)-1-Phenyl-1-butanol,97%;(R)-(+)-1-Phenyl-1-butanol, 97%;(R)-.ALPHA.-PROPYLBENZENEMETHANOL;Benzyl alcohol, alpha-propyl-, (R)-(+)-;(R)-(+)-.ALPHA.-HYDROXYBUTYLBENZENE;(R)-(+)-.ALPHA.-PROPYLBENZENEMETHANOL;(.ALPHA.R)-.ALPHA.-PROPYLBENZENEMETHANOL;BENZYL ALCOHOL, .ALPHA.-PROPYL-, (R)-(+)-;Q27259965;BENZENEMETHANOL, .ALPHA.-PROPYL-, (.ALPHA.R)-

Suppliers and Price of (R)-(+)-1-Phenyl-1-butanol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
(R)-(+)-1-Phenyl-1-butanol 97%
1g
$ 125.00

American Custom Chemicals Corporation
(R)-(+)-1-PHENYL-1-BUTANOL 95.00%
5G
$ 1246.71

American Custom Chemicals Corporation
(R)-(+)-1-PHENYL-1-BUTANOL 95.00%
1G
$ 727.41

Total 6 raw suppliers

Chemical Property of (R)-(+)-1-Phenyl-1-butanol Edit

Chemical Property:

Vapor Pressure:0.0338mmHg at 25°C
Melting Point:44-46 °C(lit.)
Refractive Index:1.5139 (estimate)
Boiling Point:115 °C14 mm Hg(lit.)
Flash Point:103.9°C
PSA：20.23000
Density:0.978g/cm³
LogP:2.52010
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:150.104465066
Heavy Atom Count:11
Complexity:95

Purity/Quality:

97% ^*data from raw suppliers

(R)-(+)-1-Phenyl-1-butanol 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CCCC(C1=CC=CC=C1)O
Isomeric SMILES:CCC[C@H](C1=CC=CC=C1)O
Uses (R)-(+)-1-Phenyl-1-butanol can be used as a substrate in the thermodynamic studies of:Transesterification of phenyl alkanols with butyl acetate in the presence of lipase enzyme.Reduction of phenyl alkanones in the presence of ketoreductase enzyme.

Technology Process of (R)-(+)-1-Phenyl-1-butanol

There total 64 articles about (R)-(+)-1-Phenyl-1-butanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 495-40-9
propiophenone

: 22144-60-1
(R)-1-butylphenylethanol

Guidance literature:: With (2-((2,4-dimethyl-5-phenylimidazo[1,5-b]pyridazin-7-yl)amido)-4-methylpentan-1-ol)(1,5-cyclooctadiene)iridium(I); potassium tert-butylate; hydrogen; acetone; In tetrahydrofuran; at 20 ℃; for 48h; under 15.0015 Torr; optical yield given as %ee; enantioselective reaction; Autoclave;
DOI:10.1002/anie.201004665

Reference yield: 82.0%

: 2234-82-4
1-propylmagnesium chloride

: 100-52-7
benzaldehyde

: 22144-60-1
(R)-1-butylphenylethanol

: 492-70-6,655-48-1,2325-10-2,38270-73-4,52340-78-0,579-43-1
1,2-diphenyl-1,2-ethanediol

Guidance literature:: 1-propylmagnesium chloride; With titanium(IV) isopropylate; In dichloromethane; at -78 ℃; for 0.166667h; Inert atmosphere;

benzaldehyde; With (R)-3-(3,5-diphenylphenyl)-2,2'-dihydroxy-1,1'-binaphthyl; In diethyl ether; dichloromethane; at 0 ℃; for 3h; Inert atmosphere;

With hydrogenchloride; water; In diethyl ether; dichloromethane; at 0 ℃; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1246/bcsj.20090232

Reference yield: 79.0%

: 2234-82-4
1-propylmagnesium chloride

: 100-52-7
benzaldehyde

: 22144-60-1
(R)-1-butylphenylethanol

Guidance literature:: 1-propylmagnesium chloride; With titanium(IV) isopropylate; triisopropoxytitanium(IV) chloride; In diethyl ether; at -78 - 0 ℃; for 0.416667h; Inert atmosphere;

benzaldehyde; With (R)-3-(3,5-di-tert-butylphenyl)-2,2'-dihydroxy-5,5′,6,6′,7,7′,8,8′-octahydro-1,1′-binaphthyl; In 1,4-dioxane; diethyl ether; at 0 ℃; for 0.5h; enantioselective reaction; Inert atmosphere;
DOI:10.1021/acs.joc.8b00929