1,2-Dichloro-1-ethoxy-ethene

Base Information

• Chemical Name: 1,2-Dichloro-1-ethoxy-ethene
• CAS No.: 42345-82-4
• Molecular Formula: C4H6Cl2O
• Molecular Weight: 140.997
• DSSTox Substance ID: DTXSID70702605
• Mol file: 42345-82-4.mol

Synonyms:1,2-dichloro-1-ethoxy-ethene;DTXSID70702605

Chemical Property of 1,2-Dichloro-1-ethoxy-ethene

Chemical Property:

• Refractive Index: 1.4558 (estimate)
• Boiling Point: 189.51°C (rough estimate)
• PSA: 9.23000
• Density: 1.1972
• LogP: 2.29940
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 139.9795702
• Heavy Atom Count: 7
• Complexity: 70.1

Purity/Quality:

(E)-1,2-DICHLORO-1-ETHOXYETHENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=CCl)Cl

Technology Process of 1,2-Dichloro-1-ethoxy-ethene

There total 10 articles about 1,2-Dichloro-1-ethoxy-ethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

ethanol (64-17-5) + Trichloroethylene (79-01-6) → (E)-1,2-dichloro-1-ethoxy-ethene (42345-82-4)

Guidance literature:

With sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In diethyl ether; cyclohexane; dimethyl sulfoxide; for 4h; Heating;

Reference yield:

ethyl dichlorothionoacetate (112260-88-5) → (E)-1,2-dichloro-1-ethoxy-ethene (42345-82-4) + diphenyldisulfane (882-33-7) + ethyl 1,1-dichloroacetate (535-15-9)

Guidance literature:

With dibenzoyl peroxide; In cyclohexane; at 80 ℃; for 6h; Yield given. Yields of byproduct given;

DOI:10.1007/BF00959374

Reference yield:

ethanol (64-17-5) → (E)-1,2-dichloro-1-ethoxy-ethene (42345-82-4)

Guidance literature:

With sodium hydroxide; methyllithium; calcium carbonate; und anschliessend reagieren mit Trichloraethylen;

upstream raw materials:

dichloroethyne

sodium ethanolate

ethanol

Trichloroethylene

Downstream raw materials:

chloroacetic acid ethyl ester

1,2-di(1-hydroxycyclohexyl)acetylene

1,2-bis[(1-hydroxy)cyclohexyl]ethane

3-oxapentanoic acid

Refernces

• 1、 Bogdal, Dariusz. "Application of Trichloroethylene in Organic Synthesis. X. Synthesis of 1,2-Dichlorovinyl Aliphatic Ethers". . p. 809 - 812. Retrieved 2007/10/03.