Phosphine, diphenyl[(trimethylsilyl)methyl]-

Base Information

• Chemical Name: Phosphine, diphenyl[(trimethylsilyl)methyl]-
• CAS No.: 4451-96-1
• Molecular Formula: C16H21PSi
• Molecular Weight: 272.402
• Hs Code.: 2931900090
• DSSTox Substance ID: DTXSID20477134
• Nikkaji Number: J371.534E
• Mol file: 4451-96-1.mol

Synonyms:4451-96-1;Phosphine, diphenyl[(trimethylsilyl)methyl]-;diphenyl(trimethylsilylmethyl)phosphane;(Diphenylphosphino)(trimethylsilyl)methane;Diphenyl((trimethylsilyl)methyl)phosphine;SCHEMBL10730205;DTXSID20477134;DIPHENYL(TRIMETHYLSILYLMETHYL)PHOSPHINE

Chemical Property of Phosphine, diphenyl[(trimethylsilyl)methyl]-

Chemical Property:

• Refractive Index: 1.581
• Boiling Point: 139-143°C / 0.6
• PSA: 13.59000
• LogP: 4.41500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 4
• Exact Mass: 272.11501420
• Heavy Atom Count: 18
• Complexity: 216

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)CP(C1=CC=CC=C1)C2=CC=CC=C2

Technology Process of Phosphine, diphenyl[(trimethylsilyl)methyl]-

There total 8 articles about Phosphine, diphenyl[(trimethylsilyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

chloro-diphenylphosphine (1079-66-9,74391-44-9) + Chloromethyltrimethylsilane (2344-80-1) → diphenyl(trimethylsilylmethyl)phosphane (4451-96-1)

Guidance literature:

Chloromethyltrimethylsilane; With magnesium; In tetrahydrofuran;

chloro-diphenylphosphine; at 20 ℃; for 0.5h;

DOI:10.1002/1099-0682(200209)2002:9<2477::AID-EJIC2477>3.0.CO;2-U

Reference yield: 78.0%

trimethylsilylmethyllithium (1822-00-0) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → diphenyl(trimethylsilylmethyl)phosphane (4451-96-1)

Guidance literature:

In tetrahydrofuran; for 15h; -78 deg C -> RT;

Reference yield: 76.0%

(trimethylsilyl)methylmagnesium chloride (13170-43-9) + chloro-diphenylphosphine (1079-66-9,74391-44-9) → diphenyl(trimethylsilylmethyl)phosphane (4451-96-1)

Guidance literature:

In diethyl ether; Ambient temperature;

DOI:10.1246/bcsj.64.708

upstream raw materials:

(trimethylsilyl)methylmagnesium chloride

chloro-diphenylphosphine

Chloromethyltrimethylsilane

chloro-trimethyl-silane

Downstream raw materials:

diphenylphosphine

Trimethylsilylmethyl-diphenylphosphinsulfid

(2-hydroxy-2-phenylethyl)diphenylphosphine

(2-phenyl-2-trimethylsiloxyethyl)diphenylphosphine