Methyl-(4-Methyl-pyridin-2-yl)-aMine

Base Information

• Chemical Name: Methyl-(4-Methyl-pyridin-2-yl)-aMine
• CAS No.: 45699-12-5
• Molecular Formula: C7H10N2
• Molecular Weight: 122.17
• Hs Code.: 2933399990
• Mol file: 45699-12-5.mol

Synonyms:methyl-(4-methyl-pyridin-2-yl)-amine;2-methylamino-4-methylpyridine;2-methylamino-4-picoline;4-Methyl-2-methylamino-pyridin;

Chemical Property of Methyl-(4-Methyl-pyridin-2-yl)-aMine

Chemical Property:

• PSA: 24.92000
• LogP: 1.50470

Purity/Quality:

Methyl-(4-methyl-pyridin-2-yl)-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl-(4-Methyl-pyridin-2-yl)-aMine

There total 4 articles about Methyl-(4-Methyl-pyridin-2-yl)-aMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

Benzotriazol-1-ylmethyl-(4-methyl-pyridin-2-yl)-amine (111098-30-7) → 2-(methylamino)-4-methylpyridine (45699-12-5)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; for 8h; Heating;

Reference yield: 31.0%

2-Amino-4-methylpyridine (695-34-1) + methanol (67-56-1) → 2-(methylamino)-4-methylpyridine (45699-12-5)

Guidance literature:

With Wilkinson's catalyst; benzoic acid; In toluene; for 12h; Heating;

DOI:10.1039/b814166e

Reference yield:

C7H7(2)H3N2 (1097898-01-5) → 2-(methylamino)-4-methylpyridine (45699-12-5)

Guidance literature:

With Wilkinson's catalyst; water; In toluene; at 130 ℃; for 24h;

DOI:10.1039/b814166e

upstream raw materials:

Benzotriazol-1-ylmethyl-(4-methyl-pyridin-2-yl)-amine

2-Amino-4-methylpyridine

methanol

C₇H₇⁽²⁾H₃N₂

Downstream raw materials:

5-bromo-4-methyl-2-methylaminopyridine

bis-exo-norbornylketone

1,5-dicyclohexyl-3-pentanone

5-bromo-4-methyl-2-methylamino-3-nitropyridine

Refernces

• 1、 Lindstroem, Stefan,Ahmad, Tania,Grivas, Spiros. "SYNTHESIS OF THE MUTAGENIC 2-AMINO-1,6-DIMETHYLIMIDAZOPYRIDINE (1,6-DMIP) AND FIVE OF ITS ISOMERS". . p. 529 - 540. Retrieved 2007/10/02.