4-Methoxybenzaldehyde dimethylhydrazone

Base Information

• Chemical Name: 4-Methoxybenzaldehyde dimethylhydrazone
• CAS No.: 14371-13-2
• Molecular Formula: C10H14 N2 O
• Molecular Weight: 178.234
• Hs Code.: 2928000090
• NSC Number: 155385
• Mol file: 14371-13-2.mol

Synonyms:4-Methoxybenzaldehyde dimethylhydrazone;14371-13-2;NSC 155385;BRN 2084973;Benzaldehyde, 4-methoxy-, dimethylhydrazone;N-(Dimethylamino)-4-methoxybenzenemethanimine;4-08-00-00273 (Beilstein Handbook Reference);N-[(4-methoxyphenyl)methylideneamino]-N-methylmethanamine;N-[(E)-(4-methoxyphenyl)methylideneamino]-N-methylmethanamine;WLN: 1OR D1UNN1&1;NSC155385;NSC-155385;LS-25090

Chemical Property of 4-Methoxybenzaldehyde dimethylhydrazone

Chemical Property:

• Vapor Pressure: 0.00155mmHg at 25°C
• Boiling Point: 295.2°C at 760 mmHg
• Flash Point: 132.3°C
• PSA: 24.83000
• Density: 0.96g/cm³
• LogP: 1.59070
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 178.110613074
• Heavy Atom Count: 13
• Complexity: 160

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CN(C)N=CC1=CC=C(C=C1)OC
• Isomeric SMILES: CN(C)/N=C/C1=CC=C(C=C1)OC

Technology Process of 4-Methoxybenzaldehyde dimethylhydrazone

There total 14 articles about 4-Methoxybenzaldehyde dimethylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-methoxy-benzaldehyde (123-11-5) + N,N-Dimethylhydrazine (57-14-7) → 4-methoxybenzaldehyde dimethylhydrazone (14371-13-2)

Guidance literature:

With magnesium sulfate; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1002/anie.201104544

Reference yield: 95.0%

1-(azidomethyl)-4-methoxybenzene (70978-37-9) + N,N-Dimethylhydrazine (57-14-7) → 4-methoxybenzaldehyde dimethylhydrazone (14371-13-2)

Guidance literature:

iron(III) chloride; In acetonitrile; for 21h; Heating;

DOI:10.1021/jo000708w

Reference yield: 91.0%

4-methoxy-benzaldehyde (123-11-5) + N,N-Dimethylhydrazine (57-14-7) → N'-[1-(4-Methoxy-phenyl)-meth-(E)-ylidene]-N,N-dimethyl-hydrazine (14371-13-2)

Guidance literature:

With acetic acid; In ethanol; for 2h; Heating;

DOI:10.1055/s-2003-40528

upstream raw materials:

4-methoxy-benzaldehyde

N,N-Dimethylhydrazine

1-(azidomethyl)-4-methoxybenzene

4-methyl-benzaldehyde

Downstream raw materials:

3-(p-methoxyphenyl)-1,1,1-trifluoropropane-2,3-dione 3-dimethylhydrazone

4-methoxy-benzaldehyde

4-methoxy-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde N,N-dimethylhydrazone

(CH₃)4C₂O₂BC₆H₃(OCH₃)CHNN(CH₃)2