4-methyl-N-(2-phenylethylideneamino)benzenesulfonamide

Base Information

• Chemical Name: 4-methyl-N-(2-phenylethylideneamino)benzenesulfonamide
• CAS No.: 17336-58-2
• Molecular Formula: C15H16N2O2S
• Molecular Weight: 288.37
• DSSTox Substance ID: DTXSID60938370
• Mol file: 17336-58-2.mol

Synonyms:17336-58-2;DTXSID60938370;4-Methyl-N'-(2-phenylethylidene)benzene-1-sulfonohydrazide

Chemical Property of 4-methyl-N-(2-phenylethylideneamino)benzenesulfonamide

Chemical Property:

• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 288.09324893
• Heavy Atom Count: 20
• Complexity: 400

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)S(=O)(=O)NN=CCC2=CC=CC=C2

Technology Process of 4-methyl-N-(2-phenylethylideneamino)benzenesulfonamide

There total 1 articles about 4-methyl-N-(2-phenylethylideneamino)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

phenylacetaldehyde (122-78-1) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 4-methyl-N'-(2-phenylethylidene)benzenesulfonohydrazide (17336-58-2)

Guidance literature:

In neat (no solvent); at 20 ℃; for 0.0166667h;

DOI:10.1002/open.201800206

Reference yield: 89.0%

phthalimide (136918-14-4,85-41-6) + 4-methyl-N'-(2-phenylethylidene)benzenesulfonohydrazide (17336-58-2) → N-(2-phenylethyl)phthalimide (7501-05-5)

Guidance literature:

With copper(l) iodide; caesium carbonate; In 1,4-dioxane; at 110 ℃; for 3.5h; Inert atmosphere;

DOI:10.1039/c4ra05929h

Reference yield: 88.0%

4-methyl-N'-(2-phenylethylidene)benzenesulfonohydrazide (17336-58-2) + Diphenylphosphine oxide (4559-70-0) → (2-phenylethyl)diphenylphosphine oxide (3582-84-1)

Guidance literature:

With copper(l) iodide; caesium carbonate; In 1,2-dimethoxyethane; at 80 ℃; for 12h; Inert atmosphere;

DOI:10.1002/adsc.201200295

upstream raw materials:

phenylacetaldehyde

toluene-4-sulfonic acid hydrazide

Downstream raw materials:

phenylacetaldehyde

1-(trimethylsilyl)-4-phenyl-1-butyne

diethyl 2-phenylethylphosphonate

(2-phenylethyl)diphenylphosphine oxide