Technology Process of Benzoic acid, 5-methoxy-2-(methylamino)-, ethyl ester (9CI)
There total 4 articles about Benzoic acid, 5-methoxy-2-(methylamino)-, ethyl ester (9CI) which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
oxygen; palladium diacetate; copper(II) dipivaloate; potassium iodide;
In
dimethyl sulfoxide; toluene; acetonitrile;
at 90 ℃;
for 12h;
Schlenk technique;
DOI:10.1021/acs.orglett.5b00206
- Guidance literature:
-
Multi-step reaction with 4 steps
1: methanol / 6 h / 100 °C
2: sodium hydride / tetrahydrofuran / 0.02 h / 5 °C
3: hydrogenchloride / water / 120 °C
4: palladium diacetate; copper diacetate; potassium iodide; potassium acetate / N,N-dimethyl-formamide / 9 h / 100 °C / 760.05 Torr
With
hydrogenchloride; potassium acetate; copper diacetate; palladium diacetate; sodium hydride; potassium iodide;
In
tetrahydrofuran; methanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jo502581p
- Guidance literature:
-
Multi-step reaction with 3 steps
1: sodium hydride / tetrahydrofuran / 0.02 h / 5 °C
2: hydrogenchloride / water / 120 °C
3: palladium diacetate; copper diacetate; potassium iodide; potassium acetate / N,N-dimethyl-formamide / 9 h / 100 °C / 760.05 Torr
With
hydrogenchloride; potassium acetate; copper diacetate; palladium diacetate; sodium hydride; potassium iodide;
In
tetrahydrofuran; water; N,N-dimethyl-formamide;
DOI:10.1021/jo502581p
