2-Pyridyl-trimethylammonium iodide

Base Information

• Chemical Name: 2-Pyridyl-trimethylammonium iodide
• CAS No.: 33675-27-3
• Molecular Formula: C8H13N2+
• Molecular Weight: 264.109
• DSSTox Substance ID: DTXSID20460980
• NSC Number: 132334
• Mol file: 33675-27-3.mol

Synonyms:33675-27-3;2-pyridyl-trimethylammonium iodide;AGN-PC-005TY0;SCHEMBL14675423;DTXSID20460980;NSC132334;NSC-132334

Chemical Property of 2-Pyridyl-trimethylammonium iodide

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 264.01235
• Heavy Atom Count: 11
• Complexity: 104

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[N+](C)(C)C1=CC=CC=N1.[I-]

Technology Process of 2-Pyridyl-trimethylammonium iodide

There total 2 articles about 2-Pyridyl-trimethylammonium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

2-(Dimethylamino)pyridine (5683-33-0) + methyl iodide (74-88-4) → trimethylpyridin-2-ylammonium iodide (33675-27-3)

Guidance literature:

In dichloromethane; at 50 ℃; for 12h; Inert atmosphere;

DOI:10.1002/anie.201100683

Reference yield:

2-(Dimethylamino)pyridine (5683-33-0) + 1,3-Diiodopropane (627-31-6) → 1-methyl-1,2,3,4-tetrahydropyrido[1,2-a]pyrimidin-5-ylium iodide (1199223-66-9) + 2-dimethylamino-1-methylpyridinium iodide (66612-09-7) + trimethylpyridin-2-ylammonium iodide (33675-27-3)

Guidance literature:

In acetonitrile; for 48h; Reflux;

DOI:10.1021/ja908191k

Reference yield: 99.0%

trimethylpyridin-2-ylammonium iodide (33675-27-3) + p-tolylzinc(II) chloride (90252-89-4) → 2-(4-methylphenyl)pyridine (4467-06-5)

Guidance literature:

With C₃₈H₃₄Br₂N₄Ni₂P₂; potassium iodide; In tetrahydrofuran; 1-methyl-pyrrolidin-2-one; at 65 ℃; for 12h; Reagent/catalyst; Concentration; Inert atmosphere; Schlenk technique;

DOI:10.1021/om500452c

upstream raw materials:

2-(Dimethylamino)pyridine

methyl iodide

1,3-Diiodopropane

Downstream raw materials:

2-trimethylstannylpyridine

N,N-dimethyl-4-(pyridin-2-yl)aniline

2-(4-methylphenyl)pyridine

4-(2-pyridinyl)anisole