[1,1'-Biphenyl]-2-ol,4'-chloro-

Base Information

• Chemical Name: [1,1'-Biphenyl]-2-ol,4'-chloro-
• CAS No.: 64181-76-6
• Molecular Formula: C12H9 Cl O
• Molecular Weight: 204.656
• Mol file: 64181-76-6.mol

Synonyms:2-Hydroxy-4'-chlorobiphenyl;2'-Hydroxy PCB 3; 4-Chloro-2'-hydroxybiphenyl; 4'-Chloro-2-biphenylol

Chemical Property of [1,1'-Biphenyl]-2-ol,4'-chloro-

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [1,1'-Biphenyl]-2-ol,4'-chloro-

There total 4 articles about [1,1'-Biphenyl]-2-ol,4'-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1-Chloro-4-iodobenzene (637-87-6) + phenol (108-95-2,27073-41-2) → 4'-Chloro-4-biphenylol (28034-99-3) + 4-chloro-2'-hydroxybiphenyl (64181-76-6)

Guidance literature:

With silver(I) acetate; palladium diacetate; toluene-4-sulfonic acid; acetic acid; In water; at 70 ℃; for 48h; Sealed tube; Inert atmosphere;

DOI:10.1039/c5ob00132c

Reference yield: 40.0%

4-chlorophenylhydrazine hydrochloride (1073-70-7) + phenol (108-95-2,27073-41-2) → 4'-Chloro-4-biphenylol (28034-99-3) + 4-chloro-2'-hydroxybiphenyl (64181-76-6)

Guidance literature:

With manganese(IV) oxide; sodium hydroxide; In acetonitrile;

DOI:10.1021/jo301980j

Reference yield:

4-chlorophenyldiazonium salt (17333-85-6) + phenol (108-95-2,27073-41-2) → 4'-Chloro-4-biphenylol (28034-99-3) + 4-chloro-2'-hydroxybiphenyl (64181-76-6)

Guidance literature:

DOI:10.1021/ja01206a036

upstream raw materials:

4-chlorophenyldiazonium salt

phenol

4-chlorophenylhydrazine hydrochloride

1-Chloro-4-iodobenzene

Downstream raw materials:

N-(4'-Chloro-5-cyclohexylaminomethyl-6-hydroxy-biphenyl-3-yl)-acetamide

N-[5-(Adamantan-1-ylaminomethyl)-4'-chloro-6-hydroxy-biphenyl-3-yl]-acetamide

4'-Chloro-5-(7-chloro-quinolin-4-ylamino)-3-dimethylaminomethyl-biphenyl-2-ol

6-(4-chlorophenyl)-4-(7-chloroquinolin-4-ylamino)-2-diethylaminomethylphenol