2-(2,6-Dimethoxyphenyl)ethanol

Base Information

• Chemical Name: 2-(2,6-Dimethoxyphenyl)ethanol
• CAS No.: 14534-76-0
• Molecular Formula: C10H14 O3
• Molecular Weight: 182.219
• European Community (EC) Number: 668-243-0
• NSC Number: 101851
• DSSTox Substance ID: DTXSID90295428
• Nikkaji Number: J1.410.078D
• Wikidata: Q82035366
• Mol file: 14534-76-0.mol

Synonyms:2-(2,6-dimethoxyphenyl)ethanol;14534-76-0;2-(2,6-dimethoxyphenyl)ethan-1-ol;NSC101851;NCIOpen2_001901;SCHEMBL5782701;DTXSID90295428;BNHFYUPFTLMEDW-UHFFFAOYSA-N;AKOS023405501;NSC-101851;3,5-dimethoxy-4-(2-hydroxyethyl)benzene;EN300-1625510

Chemical Property of 2-(2,6-Dimethoxyphenyl)ethanol

Chemical Property:

• Vapor Pressure: 0.00156mmHg at 25°C
• Boiling Point: 282.7°C at 760 mmHg
• Flash Point: 124.8°C
• Density: 1.086g/cm³
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 182.094294304
• Heavy Atom Count: 13
• Complexity: 126

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(=CC=C1)OC)CCO

Technology Process of 2-(2,6-Dimethoxyphenyl)ethanol

There total 3 articles about 2-(2,6-Dimethoxyphenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

oxirane (75-21-8,99932-75-9) + 1,3-Dimethoxybenzene (151-10-0) → 2-(2,6-dimethoxyphenyl)ethanol (14534-76-0)

Guidance literature:

1,3-Dimethoxybenzene; With N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; at 0 ℃; for 0.5h;

With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 3h;

oxirane; In tetrahydrofuran; at 20 ℃; for 13h; Temperature; Solvent;

Reference yield:

(3,5-dimethoxyphenyl)acetic acid (4670-10-4) → 2-(2,6-dimethoxyphenyl)ethanol (14534-76-0)

Guidance literature:

With LiAlH₄; In diethyl ether;

Reference yield:

oxirane (75-21-8,99932-75-9) + (2,6-dimethoxyphenyl)lithium (2785-97-9) → 2-(2,6-dimethoxyphenyl)ethanol (14534-76-0)

Guidance literature:

DOI:10.1021/jm00324a033

upstream raw materials:

oxirane

(2,6-dimethoxyphenyl)lithium

(3,5-dimethoxyphenyl)acetic acid

1,3-Dimethoxybenzene

Downstream raw materials:

2,6-Dihydroxyphenethylalkohol

2-(2-Bromoethyl)-1,3-dimethoxybenzene

4-hydroxy-2,3-dihydrobenzofuran