DIETHYL ETHYLBROMOMALONATE

Base Information

• Chemical Name: DIETHYL ETHYLBROMOMALONATE
• CAS No.: 29237-78-3
• Molecular Formula: C9H15BrO4
• Molecular Weight: 267.12
• Hs Code.: 2917190090
• Mol file: 29237-78-3.mol

Synonyms:Malonicacid, bromoethyl-, diethyl ester (6CI,8CI);Propanedioic acid, bromoethyl-,diethyl ester (9CI);Diethyl 2-bromo-2-ethylmalonate;Diethylbromoethylmalonate;

Chemical Property of DIETHYL ETHYLBROMOMALONATE

Chemical Property:

• Vapor Pressure: 0.0149mmHg at 25°C
• Refractive Index: 1.469
• Boiling Point: 257 °C at 760 mmHg
• Flash Point: 109.2 °C
• PSA: 52.60000
• Density: 1.353 g/cm³
• LogP: 1.51380

Purity/Quality:

99% ^*data from raw suppliers

DIETHYL-(2-BROMOETHYL)MALONATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of DIETHYL ETHYLBROMOMALONATE

There total 2 articles about DIETHYL ETHYLBROMOMALONATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-2-nitropropane (5447-97-2) + Diethyl ethylsodiomalonate (18995-13-6) → ethyl 2-bromopropanedioic acid diethyl ester (29237-78-3) + 2,3-dimethyl-2,3-dinitrobutane (3964-18-9)

Guidance literature:

at 40 ℃; analog der vorangehenden Reaktion;

Reference yield:

ethanol (64-17-5) + 2-bromo-2-nitropropane (5447-97-2) + ethyl diethyl malonate (133-13-1) → ethyl 2-bromopropanedioic acid diethyl ester (29237-78-3) + 2,3-dimethyl-2,3-dinitrobutane (3964-18-9)

Guidance literature:

at 40 ℃; Reaktion der Natriumverbindung;

Reference yield: 29.0%

ethyl 2-bromopropanedioic acid diethyl ester (29237-78-3) + thioacetamide (62-55-5) → ethyl-4-hydroxy-2-methylthiazole-5-carboxylate (20737-48-8)

Guidance literature:

In toluene; for 4h; Reflux;

upstream raw materials:

2-bromo-2-nitropropane

Diethyl ethylsodiomalonate

ethanol

ethyl diethyl malonate

Downstream raw materials:

ethyl diethyl malonate

ethyl-phenoxy-malonic acid diethyl ester

ethyl-phenoxy-malonic acid

ethyl-4-hydroxy-2-methylthiazole-5-carboxylate