Methyl 2-anilinopyridine-3-carboxylate

Base Information

Chemical Name:Methyl 2-anilinopyridine-3-carboxylate
CAS No.:51269-84-2
Molecular Formula:C13H12N2O2
Molecular Weight:228.25
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70451323
Nikkaji Number:J381.266I
Wikidata:Q82271292
Mol file:51269-84-2.mol

Synonyms:51269-84-2;CHEMPACIFIC 39976;METHYL 2-PHENYLAMINONICOTINATE;Methyl 2-anilinopyridine-3-carboxylate;2-phenylamino-nicotinic acid methyl ester;Methyl 2-(phenylamino)nicotinate;methyl 2-anilinonicotinate;CHEMPACIFIC39976;SCHEMBL7281512;3-Pyridinecarboxylic acid, 2-(phenylamino)-, methyl ester;DTXSID70451323;XTQQEFBWUFUXSZ-UHFFFAOYSA-N;AKOS015962324;AM81184;methyl 2-phenylamino-3-pyridine carboxylate;FT-0727493;2-Phenylaminopyridine-3-carboxylic acid methyl ester

Suppliers and Price of Methyl 2-anilinopyridine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
METHYL 2-PHENYLAMINONICOTINATE 95.00%
100MG
$ 970.20

Total 3 raw suppliers

Chemical Property of Methyl 2-anilinopyridine-3-carboxylate

Chemical Property:

Boiling Point:158-162 °C(Press: 0.5 Torr)
PKA:3?+-.0.10(Predicted)
PSA：51.22000
Density:1.223±0.06 g/cm3(Predicted)
LogP:2.68480
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:228.089877630
Heavy Atom Count:17
Complexity:252

Purity/Quality:

99% ^*data from raw suppliers

METHYL 2-PHENYLAMINONICOTINATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)C1=C(N=CC=C1)NC2=CC=CC=C2

Technology Process of Methyl 2-anilinopyridine-3-carboxylate

There total 7 articles about Methyl 2-anilinopyridine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 40134-18-7
methyl 2-chloropyridine-3-carboxylate

: 62-53-3
aniline

: 51269-84-2
methyl 2-phenylamino-nicotinate

Guidance literature:: DOI:10.1021/jm00119a010

Reference yield: 88.0%

: 52718-95-3
2-bromonicotinic acid methyl ester

: 62-53-3
aniline

: 51269-84-2
methyl 2-phenylamino-nicotinate

Guidance literature:: With copper(l) iodide; potassium carbonate; L-proline; In toluene; at 120 ℃; for 24h; Glovebox; Inert atmosphere; Sealed tube;

Reference yield:

: 67-56-1
methanol

: 16344-24-4
2-(phenylamino)nicotinic acid

: 51269-84-2
methyl 2-phenylamino-nicotinate

Guidance literature:: 2-(phenylamino)nicotinic acid; With chloroacetonitrile; triethylamine; In acetone; for 18h; Reflux;

methanol; With sodium methylate; for 12h; Reflux;