Cyclohexanecarboxylic acid, 3-methyl-2-oxo-, ethyl ester

Base Information

Chemical Name:Cyclohexanecarboxylic acid, 3-methyl-2-oxo-, ethyl ester
CAS No.:5183-61-9
Molecular Formula:C10H16O3
Molecular Weight:184.235
Hs Code.:2918300090
Mol file:5183-61-9.mol

Synonyms:methyl (E)-4,5-epoxyhex-2-enoate;methyl 4,5-epoxy hex-2-enoate;methyl 4,5-epoxy-2(E)-hexenoate;methyl (4,5)-epoxy-(2E)-hexenoate;methyl γ,δ-epoxysorbate;methyl (E)-4,5-epoxy-2-hexenoate;

Suppliers and Price of Cyclohexanecarboxylic acid, 3-methyl-2-oxo-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of Cyclohexanecarboxylic acid, 3-methyl-2-oxo-, ethyl ester

Chemical Property:

PSA：38.83000
LogP:0.50290

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclohexanecarboxylic acid, 3-methyl-2-oxo-, ethyl ester

There total 13 articles about Cyclohexanecarboxylic acid, 3-methyl-2-oxo-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 1655-07-8
ethyl 2-oxocyclohexane carboxylate

: 74-88-4
methyl iodide

: 5183-61-9
3-methyl-2-oxo-cyclohexanecarboxylic acid ethyl ester

Guidance literature:: ethyl 2-oxocyclohexane carboxylate; With n-butyllithium; diisopropylamine; In tetrahydrofuran; at -10 ℃; for 0.5h;

methyl iodide; In tetrahydrofuran; at -10 - 30 ℃; for 6.5h;
DOI:10.1021/acs.orglett.1c01689

Reference yield:

: 1655-07-8
ethyl 2-oxocyclohexane carboxylate

: 5183-61-9
3-methyl-2-oxo-cyclohexanecarboxylic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: (methylation)

2: KOtBu / toluene

With potassium tert-butylate; In toluene;