ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate

Base Information

Chemical Name:ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate
CAS No.:53561-07-2
Molecular Formula:C18H16N2O2
Molecular Weight:292.337
Hs Code.:
DSSTox Substance ID:DTXSID20396098
Nikkaji Number:J1.819.282I
Wikidata:Q82196611
ChEMBL ID:CHEMBL1411242
Mol file:53561-07-2.mol

Synonyms:ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate;53561-07-2;ethyl 1,5-diphenylpyrazole-4-carboxylate;1,5-Diphenyl-1H-pyrazole-4-carboxylic acid ethyl ester;MLS000540977;Bionet2_000688;SCHEMBL4828987;CHEMBL1411242;DTXSID20396098;DNBJQDUHQJKJCR-UHFFFAOYSA-N;HMS1365P06;HMS2318B15;MFCD02186758;AKOS005089341;SMR000126035;ethyl1,5-diphenyl-1H-pyrazole-4-carboxylate;3R-1030;Ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate, AldrichCPR

Suppliers and Price of ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate Aldrich
1g
$ 665.00

Heterocyclics
Ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate 95%
1g
$ 375.00

Chemcia Scientific
1,5-Diphenyl-1H-pyrazole-4-carboxylicacidethylester 95%
5 G
$ 995.00

American Custom Chemicals Corporation
ETHYL 1,5-DIPHENYL-1H-PYRAZOLE-4-CARBOXYLATE 95.00%
5MG
$ 623.82

American Custom Chemicals Corporation
ETHYL 1,5-DIPHENYL-1H-PYRAZOLE-4-CARBOXYLATE 95.00%
10MG
$ 618.50

American Custom Chemicals Corporation
ETHYL 1,5-DIPHENYL-1H-PYRAZOLE-4-CARBOXYLATE 95.00%
1MG
$ 586.97

Total 6 raw suppliers

Chemical Property of ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate

Chemical Property:

Vapor Pressure:9.75E-09mmHg at 25°C
Boiling Point:462.6oC at 760 mmHg
Flash Point:233.6oC
PSA：44.12000
Density:1.14g/cm3
LogP:3.71600
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:292.121177757
Heavy Atom Count:22
Complexity:362

Purity/Quality:

98%+ ^*data from raw suppliers

Ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=C(N(N=C1)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate

There total 11 articles about ethyl 1,5-diphenyl-1H-pyrazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 59-88-1
phenylhydrazine hydrochloride

: 94-02-0
ethyl 3-oxo-3-phenylpropionate

: 53561-07-2
1,5-diphenyl-1H-pyrazole-4-carboxylic acid ethyl ester

Guidance literature:: ethyl 3-oxo-3-phenylpropionate; With N,N-dimethyl-formamide dimethyl acetal; In toluene; for 4h; Reflux;

phenylhydrazine hydrochloride; With hydrogenchloride; In butan-1-ol; for 16h; Reflux;
DOI:10.1021/acs.joc.5b02467

Reference yield: 83.0%

: 66129-60-0
ethyl-3-(dimethylamino)-2-(phenylcarbonyl)prop-2-enoate

: 100-63-0
phenylhydrazine

: 53561-07-2
1,5-diphenyl-1H-pyrazole-4-carboxylic acid ethyl ester

Guidance literature:: In ethanol; for 2h; Heating;
DOI:10.1002/jhet.5570240634

Reference yield: 78.0%

: 1294500-59-6
ethyl 1-phenyl-5-{[(trifluoromethyl)sulfonyl]oxy}-1H-pyrazole-4-carboxylate

: 98-80-6
phenylboronic acid

: 53561-07-2
1,5-diphenyl-1H-pyrazole-4-carboxylic acid ethyl ester

Guidance literature:: With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium bromide; In 1,4-dioxane; Inert atmosphere; Reflux;
DOI:10.1002/ejoc.201001560