Ethyl 5-methylbenzofuran-2-carboxylate

Base Information

Chemical Name:Ethyl 5-methylbenzofuran-2-carboxylate
CAS No.:53715-88-1
Molecular Formula:C₁₂H₁₂O₃
Molecular Weight:204.225
Hs Code.:
DSSTox Substance ID:DTXSID60523023
Wikidata:Q82388791
Mol file:53715-88-1.mol

Synonyms:ethyl 5-methylbenzofuran-2-carboxylate;53715-88-1;Ethyl 5-methyl-1-benzofuran-2-carboxylate;2-Benzofurancarboxylic acid, 5-methyl-, ethyl ester;Ethyl 5-Methyl-benzofuran-2-carboxylate;SCHEMBL1066982;DTXSID60523023;OERUTNQXHJZCDZ-UHFFFAOYSA-N;MFCD16045053;AKOS010484618;G72272;5-Methyl-benzofuran-2-carboxylic acid ethyl ester

Suppliers and Price of Ethyl 5-methylbenzofuran-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Advanced Chemicals Intermediatesced Chemicals Intermediates
5-Methyl-benzofuran-2-carboxylicacidethylester 95%+
1g
$ 427.75

Advanced Chemicals Intermediatesced Chemicals Intermediates
5-Methyl-benzofuran-2-carboxylicacidethylester 95%+
5g
$ 1297.75

Acints
5-Methyl-benzofuran-2-carboxylicacidethylester 95%+
5g
$ 1297.75

Acints
5-Methyl-benzofuran-2-carboxylicacidethylester 95%+
1g
$ 427.75

Total 6 raw suppliers

Chemical Property of Ethyl 5-methylbenzofuran-2-carboxylate

Chemical Property:

PSA：39.44000
LogP:2.91790
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:204.078644241
Heavy Atom Count:15
Complexity:239

Purity/Quality:

98% ^*data from raw suppliers

5-Methyl-benzofuran-2-carboxylicacidethylester 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(O1)C=CC(=C2)C

Technology Process of Ethyl 5-methylbenzofuran-2-carboxylate

There total 11 articles about Ethyl 5-methylbenzofuran-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 64-17-5
ethanol

: 1159343-21-1
(2-(2,2-dibromovinyl)-4-methylphenol)

: 13939-06-5,199620-15-0
molybdenum hexacarbonyl

: 53715-88-1
ethyl 5-methyl-1-benzofuran-2-carboxylate

Guidance literature:: With [2,2]bipyridinyl; triethylamine; copper(ll) bromide; at 90 ℃; for 8h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.joc.0c01620

Reference yield: 80.0%

: 613-84-3
2-hydroxy-5-methylbenzaldehyde

: 105-53-3
diethyl malonate

: 53715-88-1
ethyl 5-methyl-1-benzofuran-2-carboxylate

Guidance literature:: 2-hydroxy-5-methylbenzaldehyde; diethyl malonate; With potassium carbonate; In butanone; Reflux;

With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 1h;
DOI:10.1021/jm100556b