3-AMINO-4-(4-MORPHOLINO)BENZOTRIFLUORIDE

Base Information

Chemical Name:3-AMINO-4-(4-MORPHOLINO)BENZOTRIFLUORIDE
CAS No.:784-57-6
Molecular Formula:C11H13 F3 N2 O
Molecular Weight:246.232
Hs Code.:2934999090
Mol file:784-57-6.mol

Synonyms:m-Toluidine,a,a,a-trifluoro-6-morpholino- (7CI,8CI);2-(Morpholin-4-yl)-5-(trifluoromethyl)aniline; 2-Morpholino-5-(trifluoromethyl)aniline;3-Amino-4-(morpholino)benzotrifluoride

Suppliers and Price of 3-AMINO-4-(4-MORPHOLINO)BENZOTRIFLUORIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
N-[2-Amino-4-(trifluoromethyl)phenyl]morpholine 97%
250 mg
$ 16.00

SynQuest Laboratories
N-[2-Amino-4-(trifluoromethyl)phenyl]morpholine 97%
1 g
$ 36.00

Sigma-Aldrich
3-amino-4-(4-morpholino)benzotrifluoride Aldrich
50mg
$ 53.00

Matrix Scientific
N-[2-Amino-4-(trifluoromethyl)phenyl]-morpholine 97%
1g
$ 45.00

Crysdot
2-Morpholino-5-(trifluoromethyl)aniline 95+%
25g
$ 366.00

Chemenu
N-[2-Amino-4-(trifluoromethyl)phenyl]-morpholine 95%
25g
$ 346.00

Apolloscientific
N-[2-Amino-4-(trifluoromethyl)phenyl]morpholine 97%
1g
$ 22.00

Apolloscientific
N-[2-Amino-4-(trifluoromethyl)phenyl]morpholine 97%
250mg
$ 10.00

American Custom Chemicals Corporation
2-MORPHOLINO-5-(TRIFLUOROMETHYL)ANILINE 95.00%
5G
$ 1005.43

American Custom Chemicals Corporation
2-MORPHOLINO-5-(TRIFLUOROMETHYL)ANILINE 95.00%
2.5G
$ 852.21

Total 31 raw suppliers

Chemical Property of 3-AMINO-4-(4-MORPHOLINO)BENZOTRIFLUORIDE

Chemical Property:

Appearance/Colour:orange to pink solid
Vapor Pressure:5.02E-05mmHg at 25°C
Melting Point:127-128ºC
Boiling Point:348.5 ºC at 760 mmHg
Flash Point:164.6 ºC
PSA：38.49000
Density:1.306 g/cm³
LogP:2.77040
Storage Temp.:2-8°C(protect from light)
Water Solubility.:Insoluble in water.

Purity/Quality:

97% ^*data from raw suppliers

N-[2-Amino-4-(trifluoromethyl)phenyl]morpholine 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s): R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system
Hazard Codes:Xi,T
Statements: 36/37/38-23-21/22
Safety Statements: 26-36/37/39-36/37

MSDS Files:: SDS file from LookChem

Useful:

Uses 2-(4-Morpholinyl)-5-(trifluoromethyl)aniline is used as pharmaceutical intermediate.

Technology Process of 3-AMINO-4-(4-MORPHOLINO)BENZOTRIFLUORIDE

There total 8 articles about 3-AMINO-4-(4-MORPHOLINO)BENZOTRIFLUORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 62054-72-2
4-(2-nitro-4-trifluoromethylphenyl)morpholine

: 784-57-6
2-(morpholin-4-yl)-5-(trifluoromethyl)aniline

Guidance literature:: With hydrogenchloride; tin(ll) chloride; In methanol; at 0 - 20 ℃; for 42h;
DOI:10.1016/j.ejmech.2017.03.078

Reference yield: 94.0%

: 756833-07-5
N-[2-(morpholinyl)-5-(trifluoromethyl)phenyl]-2-pyridinecarboxamide

: 784-57-6
2-(morpholin-4-yl)-5-(trifluoromethyl)aniline

Guidance literature:: With sodium hydroxide; In ethanol; at 70 ℃; for 3h;
DOI:10.1039/d0ob00784f

Reference yield:

: 61350-01-4
N-[3-(trifluoromethyl)phenyl]-2-pyridinecarboxamide

: 784-57-6
2-(morpholin-4-yl)-5-(trifluoromethyl)aniline

Guidance literature:: Multi-step reaction with 2 steps

1: copper(l) chloride; oxygen / toluene / 12 h / 110 °C / Sealed tube

2: sodium hydroxide; ethanol / 3 h / 70 °C

With ethanol; oxygen; copper(l) chloride; sodium hydroxide; In toluene;