2-oxyethyl pyridine

Base Information

• Chemical Name: 2-oxyethyl pyridine
• CAS No.: 54765-14-9
• Molecular Formula: C7H7NO
• Molecular Weight: 121.139
• Mol file: 54765-14-9.mol

Synonyms:PYRIDIN-2-YL-ACETALDEHYDE;2-(2-pyridyl)ethanone;2-PYRIDINEACETALDEHYDE;2-(2-pyridyl)acetaldehyde;2-(PYRIDIN-2-YL)ACETALDEHYDE;

Chemical Property of 2-oxyethyl pyridine

Chemical Property:

• Boiling Point: 211.6±15.0 °C(Predicted)
• PKA: 4.62±0.12(Predicted)
• PSA: 29.96000
• Density: 1.074±0.06 g/cm3(Predicted)
• LogP: 0.82300
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

97% ^*data from raw suppliers

2-(Pyridin-2-yl)acetaldehyde 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-oxyethyl pyridine

There total 1 articles about 2-oxyethyl pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-<-(dimethylamino)ethyl>pyridine (6304-27-4) → 2‐(pyridin‐2‐yl)acetaldehyde (54765-14-9) + dimethyl amine (124-40-3)

Guidance literature:

With (batho)2Cu^II (batho = 2,9-dimethyl-4,7-diphenyl-1,10-phenanthrolinedisulfonate); water; In methanol; at 25 ℃; for 24h; Rate constant; pH 8;

DOI:10.1021/ja00027a032

Reference yield: 89.0%

2‐(pyridin‐2‐yl)acetaldehyde (54765-14-9) + 4,6-diamino-2-mercaptopyrimidine (1004-39-3) → 4,6‐bis((E)‐(2‐(pyridin‐2‐yl)ethylidene)amino)pyrimidine‐2‐thiol

Guidance literature:

In ethanol; at 60 ℃; for 6h;

DOI:10.1002/aoc.4525

Reference yield: 85.0%

2‐(pyridin‐2‐yl)acetaldehyde (54765-14-9) + 3-Amino-4-cyclohexylamino benzoic acid ethyl ester (347174-05-4) → ethyl 4-(cyclohexylamino)-3-(pyridin-2-ylmethylamino)-benzoate

Guidance literature:

2‐(pyridin‐2‐yl)acetaldehyde; 3-Amino-4-cyclohexylamino benzoic acid ethyl ester; In trans-1,2-dichloroethylene; at 80 ℃; for 1h; Molecular sieve;

With sodium tris(acetoxy)borohydride; In trans-1,2-dichloroethylene; at 20 ℃; for 17h; Inert atmosphere;

DOI:10.1021/ja411006a

upstream raw materials:

2-<-(dimethylamino)ethyl>pyridine

Downstream raw materials:

tert-butyl 5-(pyridin-2-ylmethylamino)pentylcarbamate

1-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-6-methyl-3-[2-(2-pyridin-2-yl-ethylamino)-propyl]-1H-pyrimidine-2,4-dione

1-(2,6-difluoro-benzyl)-5-(3-methoxy-phenyl)-6-methyl-3-[2-(2-pyridin-2-yl-ethylamino)-propyl]-1H-pyrimidine-2,4-dione

2-(pyridin-2-yl)-thioacetamide