2-(4-Cyanophenoxy)acetyl chloride

Base Information

Chemical Name:2-(4-Cyanophenoxy)acetyl chloride
CAS No.:55368-68-8
Molecular Formula:C9H6ClNO2
Molecular Weight:195.605
Hs Code.:
DSSTox Substance ID:DTXSID30480477
Wikidata:Q82315260

Synonyms:2-(4-Cyanophenoxy)acetyl chloride;55368-68-8;Acetyl chloride, (4-cyanophenoxy)-;SCHEMBL15647515;DTXSID30480477;VQSZCLLHOOHTKQ-UHFFFAOYSA-N

Suppliers and Price of 2-(4-Cyanophenoxy)acetyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of 2-(4-Cyanophenoxy)acetyl chloride

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:195.0087061
Heavy Atom Count:13
Complexity:225

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C#N)OCC(=O)Cl

Technology Process of 2-(4-Cyanophenoxy)acetyl chloride

There total 4 articles about 2-(4-Cyanophenoxy)acetyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1878-82-6
(4-cyanophenoxy)acetic acid

: 55368-68-8
2-(4-cyanophenoxy)acetyl chloride

Guidance literature:: With thionyl chloride;

Reference yield:

: 79-37-8
oxalyl dichloride

: 1878-82-6
(4-cyanophenoxy)acetic acid

: 55368-68-8
2-(4-cyanophenoxy)acetyl chloride

Guidance literature:: In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 30041-95-3
ethyl (4-cyano-phenoxy)-acetate

: 55368-68-8
2-(4-cyanophenoxy)acetyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; water / methanol / 1 h / 20 °C

2: thionyl chloride / N,N-dimethyl-formamide; toluene / 6 h / Reflux

With thionyl chloride; water; sodium hydroxide; In methanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/jo402599s