3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol

Base Information

Chemical Name:3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol
CAS No.:55828-88-1
Molecular Formula:C16H14N2O2
Molecular Weight:266.299
Hs Code.:2933199090
DSSTox Substance ID:DTXSID10353751
Wikidata:Q82131514
Mol file:55828-88-1.mol

Synonyms:3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol;55828-88-1;5-(4-methoxyphenyl)-2-phenyl-1H-pyrazol-3-one;SCHEMBL13166592;DTXSID10353751;MFCD02375557;STK324850;AKOS002332381;LS-09324;CS-0327246

Suppliers and Price of 3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol
1g
$ 150.00

Matrix Scientific
3-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol
0.500g
$ 120.00

Crysdot
3-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol 95+%
1g
$ 491.00

Total 7 raw suppliers

Chemical Property of 3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol

Chemical Property:

Melting Point:141-142 °C(Solv: ethanol (64-17-5); hexane (110-54-3); tetrahydrofuran (109-99-9))
Boiling Point:403.6±47.0 °C(Predicted)
PKA:2.50±0.50(Predicted)
PSA：47.02000
Density:1.19±0.1 g/cm3(Predicted)
LogP:2.84120
Storage Temp.:2-8°C
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:266.105527694
Heavy Atom Count:20
Complexity:380

Purity/Quality:

99% ^*data from raw suppliers

3-(4-Methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=CC(=O)N(N2)C3=CC=CC=C3

Technology Process of 3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol

There total 8 articles about 3-(4-methoxyphenyl)-1-phenyl-1H-pyrazol-5-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 100-63-0
phenylhydrazine

: 2881-83-6
ethyl 4-methoxybenzoylacetate

: 55828-88-1
5-(4-methoxyphenyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

Guidance literature:: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide; In ethyl acetate; at 100 ℃; for 0.0833333h; Microwave irradiation; Sealed tube;
DOI:10.1002/ejoc.201300380

Reference yield: 78.0%

: 55828-88-1
5-(4-methoxyphenyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

Guidance literature:: In ethanol; at 0 - 60 ℃; for 3h;

Reference yield: 68.0%

: 201230-82-2
carbon monoxide

: 100-63-0
phenylhydrazine

: 2196-99-8
2-chloro-1-(4-methoxyphenyl)ethanone

: 846022-60-4
5-(4'-methoxyphenyl)-1-phenyl-4-pyrazolin-3-one

: 55828-88-1
5-(4-methoxyphenyl)-2-phenyl-2,4-dihydro-3H-pyrazol-3-one

Guidance literature:: With palladium diacetate; triethylamine; triphenylphosphine; In tetrahydrofuran; at 110 ℃; for 10h; under 20521.4 Torr; regioselective reaction; Autoclave;
DOI:10.1016/j.tetlet.2016.06.072