N-[(E)-1-(4-methoxyphenyl)ethylideneamino]aniline

Base Information

• Chemical Name: N-[(E)-1-(4-methoxyphenyl)ethylideneamino]aniline
• CAS No.: 24310-46-1
• Molecular Formula: C15H16 N2 O
• Molecular Weight: 240.305
• NSC Number: 68564
• Mol file: 24310-46-1.mol

Synonyms:NSC68564;24310-46-1;SCHEMBL23392549;NSC-68564;AKOS002288974

Chemical Property of N-[(E)-1-(4-methoxyphenyl)ethylideneamino]aniline

Chemical Property:

• Vapor Pressure: 1.41E-05mmHg at 25°C
• Boiling Point: 367°C at 760 mmHg
• Flash Point: 175.8°C
• Density: 1.03g/cm³
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 240.126263138
• Heavy Atom Count: 18
• Complexity: 264

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NNC1=CC=CC=C1)C2=CC=C(C=C2)OC
• Isomeric SMILES: C/C(=N\NC1=CC=CC=C1)/C2=CC=C(C=C2)OC

Technology Process of N-[(E)-1-(4-methoxyphenyl)ethylideneamino]aniline

There total 4 articles about N-[(E)-1-(4-methoxyphenyl)ethylideneamino]aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

phenylhydrazine hydrochloride (59-88-1) + 1-(4-methoxyphenyl)ethanone (100-06-1) → 4-methoxyacetophenone phenylhydrazone (24310-46-1)

Guidance literature:

With sodium acetate; In ethanol; at 25 - 80 ℃; for 0.1h; Microwave irradiation;

DOI:10.1021/jm3013097

Reference yield: 90.0%

phenylhydrazine (100-63-0) + 1-(4-methoxyphenyl)ethanone (100-06-1) → 4-methoxyacetophenone phenylhydrazone (24310-46-1)

Guidance literature:

In ethanol; at 70 ℃; for 1h;

DOI:10.1111/cbdd.13632

Reference yield:

phenyl hydrazine hydrochloride + 1-(4-methoxyphenyl)ethanone (100-06-1) → 4-methoxyacetophenone phenylhydrazone (24310-46-1)

Guidance literature:

With sodium acetate; In ethanol; for 2h; Reflux;

DOI:10.1016/j.bioorg.2018.03.023

upstream raw materials:

phenylhydrazine

1-(4-methoxyphenyl)ethanone

phenylhydrazine hydrochloride

4-methoxyphenylacetylen

Downstream raw materials:

2-(4-methoxyphenyl)-1H-indole

3-(4-methoxyphenyl)-5-phenacyl-1-phenylpyrazole

1-phenyl-3-(4-methylphenyl)-1H-pyrazole-4-carboxaldehyde semicarbazone

1-phenyl-3-(4-methoxyphenyl)-1H-pyrazole-4-carboxaldehyde thiosemicarbazone