2-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)-4,5-dimethoxybenzamide

Base Information

Chemical Name:2-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)-4,5-dimethoxybenzamide
CAS No.:56658-13-0
Molecular Formula:C13H18BrNO4
Molecular Weight:332.194
Hs Code.:
DSSTox Substance ID:DTXSID20488265
Wikidata:Q82330825

Synonyms:56658-13-0;2-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)-4,5-dimethoxybenzamide;SCHEMBL11833693;DTXSID20488265;LMMMAMQFBVGSSV-UHFFFAOYSA-N;2-bromo-4,5-dimethoxy-N-(1-hydroxy-2-methyl-2-propyl)benzamide

Suppliers and Price of 2-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)-4,5-dimethoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)-4,5-dimethoxybenzamide

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:331.04192
Heavy Atom Count:19
Complexity:311

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(CO)NC(=O)C1=CC(=C(C=C1Br)OC)OC

Technology Process of 2-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)-4,5-dimethoxybenzamide

There total 3 articles about 2-Bromo-N-(1-hydroxy-2-methylpropan-2-yl)-4,5-dimethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55171-61-4
2-bromo-4,5-dimethoxybenzoyl chloride

: 124-68-5
2-Amino-2-methyl-1-propanol

: 56658-13-0
2-bromo-N-(2-hydroxy-1,1-dimethyl-ethyl)-4,5-dimethoxy-benzamide

Guidance literature:: With triethylamine; In 1,4-dioxane; at 0 - 20 ℃; for 1h; Inert atmosphere;
DOI:10.1021/jacs.7b13492

Reference yield:

: 6286-46-0
2-bromo-4,5-dimethoxybenzoic acid

: 56658-13-0
2-bromo-N-(2-hydroxy-1,1-dimethyl-ethyl)-4,5-dimethoxy-benzamide

Guidance literature:: Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane / 0 - 20 °C / Inert atmosphere

2: triethylamine / 1,4-dioxane / 1 h / 0 - 20 °C / Inert atmosphere

With oxalyl dichloride; triethylamine; N,N-dimethyl-formamide; In 1,4-dioxane; dichloromethane;
DOI:10.1021/jacs.7b13492