2,2,2-Trifluoroethoxytrimethylsilane

Base Information

• Chemical Name: 2,2,2-Trifluoroethoxytrimethylsilane
• CAS No.: 56859-55-3
• Molecular Formula: C5H11F3OSi
• Molecular Weight: 172.222
• DSSTox Substance ID: DTXSID00449571
• Nikkaji Number: J596.070C
• Wikidata: Q82269086
• Mol file: 56859-55-3.mol

Synonyms:2,2,2-Trifluoroethoxytrimethylsilane;56859-55-3;Trimethyl(2,2,2-trifluoroethoxy)silane;Silane, trimethyl(2,2,2-trifluoroethoxy)-;SCHEMBL5533086;Trifluoroethanol, TMS derivative;DTXSID00449571

Chemical Property of 2,2,2-Trifluoroethoxytrimethylsilane

Chemical Property:

• Boiling Point: 73.2±35.0 °C(Predicted)
• PSA: 9.23000
• Density: 1.015±0.06 g/cm3(Predicted)
• LogP: 2.40020
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 172.05312599
• Heavy Atom Count: 10
• Complexity: 104

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)OCC(F)(F)F

Technology Process of 2,2,2-Trifluoroethoxytrimethylsilane

There total 6 articles about 2,2,2-Trifluoroethoxytrimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-((trimethylsilyl)methyl)-3,5-dichlorobenzene (69380-94-5) + sodium 2,2,2-trifluoroethanolate (420-87-1) → (2,2,2-trifluoroethoxy)trimethylsilane (56859-55-3) + 3,5-dichlorotoluene (25186-47-4)

Guidance literature:

In dimethyl sulfoxide; at 50 ℃; Rate constant; var. reactant concentration and solvent system;

DOI:10.1016/S0022-328X(00)93463-6

Reference yield:

(3-chlorobenzyl)trimethylsilane (1833-42-7) + sodium 2,2,2-trifluoroethanolate (420-87-1) → 1-chloro-3-methylbenzene (108-41-8) + (2,2,2-trifluoroethoxy)trimethylsilane (56859-55-3)

Guidance literature:

In dimethyl sulfoxide; at 50 ℃; Rate constant; var. reactant concentrations;

DOI:10.1016/S0022-328X(00)93463-6

Reference yield:

2,2,2-trifluoroethanol (75-89-8) + cis-2-(trimethylsilyl)cyclohexyl trifluoroacetate (80866-33-7) → (2,2,2-trifluoroethoxy)trimethylsilane (56859-55-3) + trifluoroacetic acid (76-05-1) + cyclohexene (110-83-8)

Guidance literature:

at 25 ℃; Rate constant; other temperature (50 deg C); solvolysis of β-silyl systems, conformation effect;

DOI:10.1021/ja00371a039

upstream raw materials:

2,2,2-trifluoroethanol

cis-2-(trimethylsilyl)cyclohexyl trifluoroacetate

trans-2-(trimethylsilyl)cyclohexyl trifluoroacetate

trimethylsilyldiphenylmethane

Downstream raw materials:

2,2,2-Trifluorethoxy-phenyl-trifluorphosphoran

2,2,2-trifluoroethoxypentafluorobenzene

1,4-di-2,2,2-trifluoroethoxytetrafluorobenzene

hexakis(2,2,2-trifluoroethoxy)cyclotriphosphazene