(-)-3,4-Dimethoxy-α-[1-[2-methoxy-4-[tetrahydro-5-(4-hydroxy-3-methoxyphenyl)-3,4-dimethylfuran-2-yl]phenoxy]ethyl]benzenemethanol

Base Information

Chemical Name:(-)-3,4-Dimethoxy-α-[1-[2-methoxy-4-[tetrahydro-5-(4-hydroxy-3-methoxyphenyl)-3,4-dimethylfuran-2-yl]phenoxy]ethyl]benzenemethanol
CAS No.:88497-86-3
Molecular Formula:C31H38O8
Molecular Weight:538.638
Hs Code.:
Mol file:88497-86-3.mol

Synonyms:saucerneol;4-((2S,3R,4R,5S)-5-{4-[(1R,2R)-2-(3,4-Dimethoxy-phenyl)-2-hydroxy-1-methyl-ethoxy]-3-methoxy-phenyl}-3,4-dimethyl-tetrahydro-furan-2-yl)-2-methoxy-phenol;

Suppliers and Price of (-)-3,4-Dimethoxy-α-[1-[2-methoxy-4-[tetrahydro-5-(4-hydroxy-3-methoxyphenyl)-3,4-dimethylfuran-2-yl]phenoxy]ethyl]benzenemethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Arctom
Saucerneol ≥98%
5mg
$ 413.00

Total 0 raw suppliers

Chemical Property of (-)-3,4-Dimethoxy-α-[1-[2-methoxy-4-[tetrahydro-5-(4-hydroxy-3-methoxyphenyl)-3,4-dimethylfuran-2-yl]phenoxy]ethyl]benzenemethanol

Chemical Property:

Boiling Point:687.9±55.0 °C(Predicted)
PKA:9.91±0.35(Predicted)
PSA：95.84000
Density:1.173±0.06 g/cm3(Predicted)
LogP:6.01230

Purity/Quality:: Saucerneol ≥98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-3,4-Dimethoxy-α-[1-[2-methoxy-4-[tetrahydro-5-(4-hydroxy-3-methoxyphenyl)-3,4-dimethylfuran-2-yl]phenoxy]ethyl]benzenemethanol

There total 8 articles about (-)-3,4-Dimethoxy-α-[1-[2-methoxy-4-[tetrahydro-5-(4-hydroxy-3-methoxyphenyl)-3,4-dimethylfuran-2-yl]phenoxy]ethyl]benzenemethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 915158-83-7
(1R,2R)-2-{4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenoxy}-1-(3,4-dimethoxy-phenyl)-propan-1-ol

: 88497-86-3
sancerneol

Guidance literature:: With hydrogen; palladium dihydroxide; In ethyl acetate; at 20 ℃; for 1h;
DOI:10.1021/ol0621710

Reference yield:

: 915158-67-7
4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenol

: 88497-86-3
sancerneol

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / BEMP / CH₂Cl₂ / -45 - 0 °C

2: 95 percent / Me₂AlCl / CH₂Cl₂; hexane / 1 h / 20 °C

3: 96 percent / tetrahydrofuran / -30 - 0 °C

4: 75 percent / Amberlite IRA-400-supported borohydride / methanol / 16 h / 20 °C

5: 94 percent / H₂ / Pd(OH)2/C / ethyl acetate / 1 h / 20 °C

With Amberlite IRA-400-supported borohydride; hydrogen; dimethylaluminum chloride; 2-tert-butylimino-2-diethylamino-1,3-dimethyl-perhydro-1,3,2-diazaphosphorine; palladium dihydroxide; In tetrahydrofuran; methanol; hexane; dichloromethane; ethyl acetate;
DOI:10.1021/ol0621710

Reference yield:

: 915158-70-2
(R)-2-{4-[(2S,3R,4R,5S)-5-(4-Benzyloxy-3-methoxy-phenyl)-3,4-dimethyl-tetrahydro-furan-2-yl]-2-methoxy-phenoxy}-propionic acid methyl ester

: 88497-86-3
sancerneol

Guidance literature:: Multi-step reaction with 4 steps

1: 95 percent / Me₂AlCl / CH₂Cl₂; hexane / 1 h / 20 °C

2: 96 percent / tetrahydrofuran / -30 - 0 °C

3: 75 percent / Amberlite IRA-400-supported borohydride / methanol / 16 h / 20 °C

4: 94 percent / H₂ / Pd(OH)2/C / ethyl acetate / 1 h / 20 °C

With Amberlite IRA-400-supported borohydride; hydrogen; dimethylaluminum chloride; palladium dihydroxide; In tetrahydrofuran; methanol; hexane; dichloromethane; ethyl acetate;
DOI:10.1021/ol0621710