Benzyl 2-[(pyridin-2-yl)oxy]propanoate

Base Information

Chemical Name:Benzyl 2-[(pyridin-2-yl)oxy]propanoate
CAS No.:605680-44-2
Molecular Formula:C15H15NO3
Molecular Weight:257.289
Hs Code.:
DSSTox Substance ID:DTXSID60582635

Synonyms:605680-44-2;Benzyl 2-[(pyridin-2-yl)oxy]propanoate;Benzyl 2-(2-Pyridyloxy)propionate;SCHEMBL3370056;DTXSID60582635;ZVKCIDZFHPKTAH-UHFFFAOYSA-N

Suppliers and Price of Benzyl 2-[(pyridin-2-yl)oxy]propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzyl 2-[(pyridin-2-yl)oxy]propanoate

Chemical Property:

XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:257.10519334
Heavy Atom Count:19
Complexity:277

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)OCC1=CC=CC=C1)OC2=CC=CC=N2

Technology Process of Benzyl 2-[(pyridin-2-yl)oxy]propanoate

There total 1 articles about Benzyl 2-[(pyridin-2-yl)oxy]propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 142-08-5
2-hydroxypyridin

: 2051-96-9
benzyl lactate

: 605680-44-2
benzyl 2-(2-pyridyloxy)propionate

Guidance literature:: With triphenylphosphine; diethylazodicarboxylate; In dichloromethane; at 0 - 20 ℃; for 4h;
DOI:10.1021/jm060996+

Reference yield:

: 605680-44-2
benzyl 2-(2-pyridyloxy)propionate

: 75-03-6
ethyl iodide

: 605680-45-3
benzyl 2-(2-pyridyloxy)-2-methylbutanoate

Guidance literature:: With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 - 20 ℃; for 2h;

Reference yield:

: 605680-44-2
benzyl 2-(2-pyridyloxy)propionate

: N-[(1S,2S)-3-(4-Chloro-phenyl)-1-methyl-2-phenyl-propyl]-2-methyl-2-(pyridin-2-yloxy)-propionamide

Guidance literature:: Multi-step reaction with 4 steps

1: potassium hexamethyldisilazide / tetrahydrofuran; toluene / 2 h / -78 - 20 °C

2: 93 percent / H₂ / Pd/C / methanol / 20 °C

3: oxalyl chloride; DMF / CH₂Cl₂ / 1 h / 20 °C

4: N-methylmorpholine / CH₂Cl₂ / 6 h / 20 °C

With 4-methyl-morpholine; oxalyl dichloride; hydrogen; potassium hexamethylsilazane; N,N-dimethyl-formamide; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1021/jm060996+