2-(Isopropyl)isonicotinonitrile

Base Information

Chemical Name:2-(Isopropyl)isonicotinonitrile
CAS No.:33538-10-2
Molecular Formula:C9H10 N2
Molecular Weight:146.192
Hs Code.:
European Community (EC) Number:251-567-8
DSSTox Substance ID:DTXSID30187191
Nikkaji Number:J247.533B
Wikidata:Q83058773
Mol file:33538-10-2.mol

Synonyms:2-isopropylisonicotinonitrile;33538-10-2;2-(Isopropyl)isonicotinonitrile;2-propan-2-ylpyridine-4-carbonitrile;4-cyano-2-isopropylpyridine;EINECS 251-567-8;MFCD18384684;SCHEMBL2625459;DTXSID30187191;2-Isopropylpyridine-4-carbonitrile;GS2353;SB52672;CS-16673;SY263213;CS-0102143;F52586

Suppliers and Price of 2-(Isopropyl)isonicotinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
2-Isopropylisonicotinonitrile 95%+
250mg
$ 267.00

Chemenu
2-Isopropylisonicotinonitrile 95%+
100mg
$ 149.00

Chemenu
2-Isopropylisonicotinonitrile 95%+
1g
$ 619.00

Alichem
2-Isopropylisonicotinonitrile
5g
$ 1624.08

Alichem
2-Isopropylisonicotinonitrile
10g
$ 2436.12

Alichem
2-Isopropylisonicotinonitrile
25g
$ 3979.80

AK Scientific
2-(Isopropyl)isonicotinonitrile
1g
$ 532.00

AccelPharmtech
2-(1-methylethyl)-4-Pyridinecarbonitrile 97.00%
5G
$ 2750.00

AccelPharmtech
2-(1-methylethyl)-4-Pyridinecarbonitrile 97.00%
1G
$ 2370.00

Total 8 raw suppliers

Chemical Property of 2-(Isopropyl)isonicotinonitrile

Chemical Property:

Vapor Pressure:0.22mmHg at 25°C
Boiling Point:207.9°Cat760mmHg
PKA:2.49±0.10(Predicted)
Flash Point:85.8°C
Density:1.02g/cm³
XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:146.084398327
Heavy Atom Count:11
Complexity:166

Purity/Quality:

97% ^*data from raw suppliers

2-Isopropylisonicotinonitrile 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1=NC=CC(=C1)C#N

Technology Process of 2-(Isopropyl)isonicotinonitrile

There total 9 articles about 2-(Isopropyl)isonicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 100-48-1
pyridine-4-carbonitrile

: 72-18-4,25609-85-2,7004-03-7,921-10-8
L-valine

: 33538-10-2
2-isopropylisonicotinonitrile

: 33538-08-8
2,6-bis(1-methylethyl)-4-cyanopyridine

Guidance literature:: pyridine-4-carbonitrile; L-valine; With ammonium peroxydisulfate; water; trifluoroacetic acid; In 1,2-dichloro-ethane; at 23 ℃; for 0.0166667h;

With silver nitrate; In 1,2-dichloro-ethane; at 80 ℃; for 24h;
DOI:10.1021/acs.orglett.6b01754

Reference yield: 46.0%

: 100-48-1
pyridine-4-carbonitrile

: 79-31-2
isobutyric Acid

: 33538-10-2
2-isopropylisonicotinonitrile

: 33538-08-8
2,6-bis(1-methylethyl)-4-cyanopyridine

Guidance literature:: pyridine-4-carbonitrile; isobutyric Acid; With ammonium persulfate; Selectfluor; trifluoroacetic acid; In dichloromethane; water; at 20 ℃; for 0.0166667h;

With silver nitrate; In dichloromethane; water; at 50 ℃; Solvent; Catalytic behavior;
DOI:10.1021/acs.orglett.7b02706

Reference yield: 41.0%

: 644-98-4
2-isopropylpyridine

: 7677-24-9
trimethylsilyl cyanide

: 33538-10-2
2-isopropylisonicotinonitrile

: 337904-76-4
6-isopropylpyridine-2-carbonitrile

Guidance literature:: 2-isopropylpyridine; With trifluoromethylsulfonic anhydride; In chloroform; at 20 ℃; for 1h; Inert atmosphere; Sealed tube;

trimethylsilyl cyanide; In chloroform; at 60 ℃; for 3h; Inert atmosphere; Sealed tube;

With 4-methyl-morpholine; In chloroform; at 60 ℃; for 17h; Overall yield = 58 %; Inert atmosphere; Sealed tube;
DOI:10.1002/chem.201703931